Novel and Multi-Locus Sequence Types (MLST) of Staphylococcus Aureus Samples Isolated from Clinical Specimens in Korean.

bacteremia is one of the most frequent and severe bacterial infections worldwide. The increased incidence of infections with a diverse pattern of protein A () types across different geographic regions is a global challenge. This study investigated a novel type of methicillin-resistant in a clinically isolated specimen. A total of 109 clinical samples were subjected to 19 sets of antimicrobial susceptibility testing using the Kirby-Bauer disk diffusion method. Molecular typing was performed with protein A () and multi-locus sequence types (MLST) via polymerase chain reaction and sequencing. The methicillin-resistant samples in our study accounted for 55.05% (60/109) of the total. A novel type was detected in five (5/60) strains. This 2 isolate was identified in antimicrobial susceptibility tests of 15 kinds of antibiotics. Antibiotic resistance genes included , , and Eleven samples were classified as , , , , five unknown types (new types), and undefined MLST (novel MLST). We report a high prevalence rate of methicillin-resistant samples in our country. Additionally, novel 2, MLST ST4613, and clonal compact CC5-type strains (T1:M1:B1:B1:M1:E1:K1, r26:r17:r34:r34:r17:r13:r16, mlst;1:4:1:4:559:495:10) showing multidrug resistance were identified among samples.