Chi Felicia W, Weisner Constance M, Mertens Jennifer R, Ross Thekla B, Sterling Stacy A
Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612, USA.
Division of Research, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612, USA; Department of Psychiatry, University of California, San Francisco, 401 Parnassus Ave., San Francisco, CA, 94143, USA.
J Subst Abuse Treat. 2017 Jun;77:45-51. doi: 10.1016/j.jsat.2017.03.009. Epub 2017 Mar 22.
In clinical trials alcohol brief intervention (BI) in adult primary care has been efficacious in reducing alcohol consumption, but we know little about its impact on health outcomes. Hypertension is a prevalent and costly chronic condition in the U.S. and worldwide, and alcohol use is a modifiable hypertension risk factor.
To evaluate the effect of receiving BI for unhealthy drinking on blood pressure (BP) control among adult hypertensive patients by analyzing secondary data from a clustered, randomized controlled trial on alcohol screening, brief intervention and referral to treatment (SBIRT) implementation by primary care physicians (PCP intervention arm) and non-physician providers and medical assistants (NPP&MA intervention arm) in a large, integrated health care delivery system.
Observational, prospective cohort study.
3811 adult hypertensive primary care patients screening positive for past-year heavy drinking at baseline, of which 1422 (37%) had an electronic health record BP measure at baseline and 18-month follow-up.
Change in BP and controlled BP (systolic/diastolic BP <140/90mmHg).
Overall no significant associations were found between alcohol BI and BP change at 18-month follow-up when analyzing the combined sample of subjects in both intervention arms. However, moderation analyses found that receiving BI for positive past-year unhealthy drinking was positively associated with better BP control at 18months in the PCP intervention arm, and for those with lower heavy drinking frequency and poor BP control at the index screening.
Our findings suggest that hypertensive patients may benefit from receiving physician brief intervention for unhealthy alcohol use in primary care. Findings also highlight potential population-level benefits of alcohol BI if widely applied, suggesting a need for the development of innovative strategies to facilitate SBIRT delivery in primary care settings.
在临床试验中,成人初级保健中的酒精简短干预(BI)在减少酒精消费方面已被证明是有效的,但我们对其对健康结果的影响知之甚少。高血压在美国和全球都是一种普遍且代价高昂的慢性病,而饮酒是一个可改变的高血压风险因素。
通过分析来自一项集群随机对照试验的二次数据,评估针对不健康饮酒接受BI对成年高血压患者血压(BP)控制的影响。该试验由初级保健医生(PCP干预组)以及非医生提供者和医疗助理(NPP&MA干预组)在一个大型综合医疗保健系统中实施酒精筛查、简短干预和转介治疗(SBIRT)。
观察性前瞻性队列研究。
3811名成年高血压初级保健患者,在基线时筛查出过去一年大量饮酒呈阳性,其中1422名(37%)在基线和18个月随访时有电子健康记录血压测量值。
血压变化和血压得到控制(收缩压/舒张压<140/90mmHg)。
在分析两个干预组受试者的合并样本时,总体上在18个月随访时未发现酒精BI与血压变化之间存在显著关联。然而,调节分析发现,在PCP干预组中,针对过去一年阳性不健康饮酒接受BI与18个月时更好的血压控制呈正相关,对于那些在指数筛查时重度饮酒频率较低且血压控制不佳的患者也是如此。
我们的研究结果表明,高血压患者可能从初级保健中接受医生针对不健康饮酒的简短干预中获益。研究结果还强调了如果广泛应用酒精BI可能带来的潜在人群层面的益处,这表明需要制定创新策略以促进在初级保健环境中实施SBIRT。