Firoozabadi Reza, Gregg Richard E, Babaeizadeh Saeed
Advanced Algorithm Research Center, Philips Healthcare, Andover, MA, USA.
Advanced Algorithm Research Center, Philips Healthcare, Andover, MA, USA.
J Electrocardiol. 2017 Sep-Oct;50(5):615-619. doi: 10.1016/j.jelectrocard.2017.04.013. Epub 2017 Apr 25.
A large number of ST-elevation notifications are generated by cardiac monitoring systems, but only a fraction of them is related to the critical condition known as ST-segment elevation myocardial infarction (STEMI) in which the blockage of coronary artery causes ST-segment elevation. Confounders such as acute pericarditis and benign early repolarization create electrocardiographic patterns mimicking STEMI but usually do not benefit from a real-time notification. A STEMI screening algorithm able to recognize those confounders utilizing capabilities of diagnostic ECG algorithms in variation analysis of ST segments helps to avoid triggering a non-actionable ST-elevation notification. However, diagnostic algorithms are generally designed to analyze short ECG snapshots collected in low-noise resting position and hence are susceptible to high levels of noise common in a monitoring environment. We developed a STEMI screening algorithm which performs a real-time signal quality evaluation on the ECG waveform to select the segments with quality high enough for subsequent analysis by a diagnostic ECG algorithm. The STEMI notifications generated by this multi-stage STEMI screening algorithm are significantly fewer than ST-elevation notifications generated by a continuous ST monitoring strategy.
心脏监测系统会产生大量的ST段抬高警报,但其中只有一小部分与称为ST段抬高型心肌梗死(STEMI)的危急状况相关,在这种情况下冠状动脉阻塞会导致ST段抬高。诸如急性心包炎和良性早期复极等混杂因素会产生模仿STEMI的心电图模式,但通常无法从实时警报中受益。一种能够利用诊断性心电图算法对ST段进行变异分析的功能来识别这些混杂因素的STEMI筛查算法,有助于避免触发不可采取行动的ST段抬高警报。然而,诊断算法通常旨在分析在低噪声静息位置采集的短心电图快照,因此容易受到监测环境中常见的高水平噪声的影响。我们开发了一种STEMI筛查算法,该算法对心电图波形进行实时信号质量评估,以选择质量足够高的片段,供诊断性心电图算法进行后续分析。这种多阶段STEMI筛查算法生成的STEMI警报明显少于连续ST监测策略生成的ST段抬高警报。