Leger Paul, Limper Andrew H, Maldonado Fabien
Division of Internal Medicine, Vanderbilt University Medical Center, T1218 Medical Center North, Nashville, TN 37232-2650, USA.
Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Clin Chest Med. 2017 Jun;38(2):209-222. doi: 10.1016/j.ccm.2017.01.002. Epub 2017 Mar 1.
Despite significant recent progress in precision medicine and immunotherapy, conventional chemotherapy remains the cornerstone of the treatment of most cancers. Chemotherapy-induced lung toxicity represents a serious diagnostic challenge for health care providers and requires careful consideration because it is a diagnosis of exclusion with significant impact on therapeutic decisions. This review aims to provide clinicians with a valuable guide in assessing their patients with possible chemotherapy-induced lung toxicity.
尽管近年来精准医学和免疫疗法取得了重大进展,但传统化疗仍然是大多数癌症治疗的基石。化疗引起的肺部毒性对医疗保健提供者来说是一个严峻的诊断挑战,需要仔细考虑,因为这是一种排除性诊断,对治疗决策有重大影响。本综述旨在为临床医生评估可能患有化疗引起的肺部毒性的患者提供有价值的指导。