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抑郁症与更年期:关键时期的当前认知与临床建议

Depression and Menopause: Current Knowledge and Clinical Recommendations for a Critical Window.

作者信息

Soares Claudio N

机构信息

Department of Psychiatry, Queen's University School of Medicine, 76 Stuart Street, Kingston, Ontario K7L 2V7, Canada; Canadian Biomarker Integration Network in Depression (CAN-BIND), Department of Psychiatry, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

出版信息

Psychiatr Clin North Am. 2017 Jun;40(2):239-254. doi: 10.1016/j.psc.2017.01.007. Epub 2017 Mar 6.

DOI:10.1016/j.psc.2017.01.007
PMID:28477650
Abstract

Depression is a disabling condition, which often leads to significant personal, societal, and economic costs. Windows of vulnerability for depression in women likely are associated with an increased sensitivity experienced by some women to changes in the hormonal milieu that occur during the luteal phase of their cycles, during the postpartum period, and/or during the menopause transition. The controversy surrounding a menopause-related depression has been fueled by conflicting methodologies used to characterize reproductive staging or assess psychiatric conditions during midlife years.

摘要

抑郁症是一种使人丧失能力的疾病,常常导致巨大的个人、社会和经济代价。女性抑郁症的易患期可能与一些女性对其月经周期黄体期、产后时期和/或更年期过渡期间发生的激素环境变化更为敏感有关。围绕更年期相关抑郁症的争议因用于描述生殖阶段或评估中年时期精神状况的相互矛盾的方法而加剧。

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