Shaĭkhin S M, Muratova M V, Belov A A, Khropov Iu V, Kulagin S V
Biokhimiia. 1988 Aug;53(8):1357-64.
Several W-7 analogs were synthesized. These compounds were shown to inhibit the calmodulin-activated phosphodiesterase. A comparative analysis of kinetic parameters of W-7 and its analogs was carried out. A hypothetical model of the effects of calmodulin inhibitors is proposed.
合成了几种W-7类似物。这些化合物被证明能抑制钙调蛋白激活的磷酸二酯酶。对W-7及其类似物的动力学参数进行了比较分析。提出了钙调蛋白抑制剂作用的假设模型。
