Pozdniakova A L
Biull Eksp Biol Med. 1988 Oct;106(10):393-5.
Ouabain, used in 5.10(-4) M concentration, elicits 12 +/- 5 mV (15 experiments) depolarization of membrane of snail Helix neurons. In 80% of experiments depolarization is not accompanied by changes in membrane conductance, in 20% of experiments the decrease of the membrane conductance is observed. Application of the antibodies to S-100 protein (their concentration in the micropipette being 0.05 mg/ml) induces similar effects. The effects of ouabain and antibodies to S-100 protein are not additive and the main difference in their action lies in the ability of the cell to recover the resting potential of the membrane in the solution containing ouabain.
哇巴因以5.10（-4）M的浓度使用时，可引起蜗牛Helix神经元膜去极化12±5 mV（15次实验）。在80%的实验中，去极化不伴有膜电导的变化，在20%的实验中，观察到膜电导降低。应用抗S-100蛋白抗体（微量移液器中的浓度为0.05 mg/ml）可诱导类似效应。哇巴因和抗S-100蛋白抗体的效应不是相加的，它们作用的主要差异在于细胞在含有哇巴因的溶液中恢复膜静息电位的能力。
