Department of Orthopedics, The People's Hospital of Cangzhou, Cangzhou 061000, China.
Department of Orthopedics, The People's Hospital of Cangzhou, Cangzhou 061000, China.
Int J Surg. 2017 Jun;42:143-146. doi: 10.1016/j.ijsu.2017.04.059. Epub 2017 May 3.
To investigate the clinical effect of vacuum sealing drainage in dermatoplasty of large area of cutaneous defects in comparison to conventional treatment.
80 patients with large area of cutaneous defects were enrolled in this study, and they had received superficial thickness dermatoplasty. Then these patients were randomly divided into two groups based on follow-up treatments: vacuum sealing drainage (defined as group A, 40 cases) and conventional treatment (defined as group B, 40 cases). After operation, all the patients received similar hospital stay, antibiotics administration, swelling elimination and wound closure in these two groups.
No significant difference was observed in terms of the baseline characteristics between the two groups, including areas of cutaneous defects. Compared with conventional treatment group, the healing time of dermatoplasty was reduced significantly in vacuum sealing drainage group. Meanwhile, the rate of survival of dermatoplasty was better, and the rate of wound infection was lower in vacuum sealing drainage group than conventional treatment group.
Vacuum sealing drainage is effective in treatment with large area of cutaneous defects combined with dermatoplasty, which had better clinical outcomes than conventional therapy.
研究比较真空密封引流在大面积皮肤缺损皮瓣移植中的临床效果与传统治疗方法。
选择 80 例大面积皮肤缺损患者,行薄层皮片移植术,根据术后随访治疗方法不同分为两组,分别为真空密封引流组(A 组,40 例)和常规治疗组(B 组,40 例)。两组患者术后均给予相同的住院时间、抗生素使用、消肿及创面闭合处理。
两组患者在皮肤缺损面积等一般基线资料上无明显差异,与常规治疗组相比,真空密封引流组皮瓣移植的愈合时间明显缩短,皮瓣成活率更高,创面感染率更低。
真空密封引流治疗大面积皮肤缺损联合皮瓣移植效果确切,优于传统疗法。