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封闭式负压引流联合植皮术治疗深度烧伤的效果及术后感染危险因素分析

Effect of vacuum sealing drainage plus skin grafting on deep burns and analysis of risk factors for postoperative infection.

作者信息

Jiao Hongbo, Tian Tian, Chen Chuanjun, Ji Geng

机构信息

Burn and Plastic Surgery, Taizhou People's Hospital No. 366 Taihu Road, Hailing District, Taizhou 225300, Jiangsu, China.

出版信息

Am J Transl Res. 2022 Oct 15;14(10):7477-7486. eCollection 2022.

Abstract

OBJECTIVE

To analyze the effect of vacuum sealing drainage (VSD) plus skin grafting on deep burns and the risk factors of postoperative infection.

METHODS

A retrospective analysis was conducted on 124 patients with deep burns who were admitted to the Taizhou People's Hospital from February 2019 to February 2021. The 55 patients who underwent traditional dressing change therapy plus second-stage skin grafting became the control group. The remaining 69 patients treated with first stage VSD plus second-stage skin grafting became the observation group. Wound healing time, hospital stay, postoperative infection, wound closure success rate, pain degree, and scar hyperplasia were recorded and compared between the two groups. Logistic regression was used to analyze the risk factors of postoperative infection in patients.

RESULTS

Compared with the control group, the observation group had a shorter time of wound healing and hospital stay, lower postoperative wound infection rate and lung infection rate, higher success rate of wound closure, lower pain degree scores on the 7th day after the operation, and less scar hyperplasia (all P<0.05). Logistic regression analysis revealed that burn degree, treatment plan, proportion of burn area, and wound healing time were the factors affecting postoperative infection in patients.

CONCLUSION

VSD plus skin grafting have significant effects on deep burns. This combined treatment reduced the occurrence of the wound infection, relieved pain, shortened the healing time and hospitalization time, and reduced the proliferation of scars in the later stage.

摘要

目的

分析封闭式负压引流(VSD)联合植皮术对深度烧伤的治疗效果及术后感染的危险因素。

方法

回顾性分析2019年2月至2021年2月在泰州市人民医院收治的124例深度烧伤患者。55例行传统换药治疗联合二期植皮术的患者作为对照组。其余69例采用一期VSD联合二期植皮术治疗的患者作为观察组。记录并比较两组患者的创面愈合时间、住院时间、术后感染情况、创面封闭成功率、疼痛程度及瘢痕增生情况。采用Logistic回归分析患者术后感染的危险因素。

结果

与对照组相比,观察组创面愈合时间及住院时间短,术后创面感染率及肺部感染率低,创面封闭成功率高,术后第7天疼痛程度评分低,瘢痕增生少(均P<0.05)。Logistic回归分析显示,烧伤程度、治疗方案、烧伤面积比例及创面愈合时间是影响患者术后感染的因素。

结论

VSD联合植皮术对深度烧伤有显著疗效。这种联合治疗减少了创面感染的发生,减轻了疼痛,缩短了愈合时间和住院时间,并减少了后期瘢痕的增生。

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