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应用简易皮肤牵张系统联合负压伤口疗法修复复杂糖尿病足创面

Application of a simple skin stretching system and negative pressure wound therapy in repair of complex diabetic foot wounds.

机构信息

Department of Orthopedics, Hwa Mei Hospital, University of Chinese Academy of Sciences (Ningbo No. 2 Hospital), No. 41 Northwest Street, Ningbo, 315010, Zhejiang, China.

出版信息

J Orthop Surg Res. 2021 Apr 14;16(1):258. doi: 10.1186/s13018-021-02405-6.

Abstract

The management of complex diabetic foot wounds with large skin defects poses a challenge for surgeons. We presented a simple skin stretching system and negative pressure wound therapy for the repair of complex diabetic foot wounds to examine the effectiveness and safety.A total of 16 patients with diabetic foot ulcers were retrospectively reviewed between January 2015 and October 2020. All patients underwent the treatment by 3 stages. In stage 2, these difficult-to-close wounds of diabetes foot were residual. This method was applied to the wounds with a median defect size of 20.42 cm (range, 4.71-66.76 cm).The median time for closure of complex diabetic foot wounds was 14 days ranging from 8 to 19 days. With respect to the absolute rates of reduction, it was observed with a median of 1.86 cm/day, ranging from 0.29 cm/day to 8.35 cm/day. In accordance with the localization of the defect, the patients were divided into 3 groups: side of the foot (37.5%), dorsum of the foot (50.0%), and others (12.5%). There was no statistical difference between side of the foot and dorsum of the foot in terms of the median defect size with P = 0.069 (Kruskal-Wallis test). Otherwise, there were statistically significant differences regarding the median time and the median absolute rates (P < 0.05; Kruskal-Wallis test). No severe complications were encountered in this study.In summary, our results show that application of the simple skin stretching system and NPWT is an effective and safe approach to complex diabetic foot wounds. Nevertheless, more attention should be paid to the appropriate patient selection and intraoperative judgment to ensure wound closure and avoid undue complications.

摘要

对于外科医生来说,处理伴有大面积皮肤缺损的复杂糖尿病足创面是一个挑战。我们提出了一种简单的皮肤拉伸系统和负压伤口治疗来修复复杂的糖尿病足创面,以检验其有效性和安全性。回顾性分析 2015 年 1 月至 2020 年 10 月期间收治的 16 例糖尿病足溃疡患者,所有患者均经 3 个阶段治疗。第 2 阶段,糖尿病足这些难以闭合的伤口仍有残留。该方法应用于创面缺损中位大小为 20.42cm(范围 4.71-66.76cm)的患者。复杂糖尿病足创面的中位闭合时间为 14 天,范围为 8-19 天。就绝对减少率而言,观察到中位值为 1.86cm/天,范围为 0.29cm/天至 8.35cm/天。根据缺损的定位,将患者分为 3 组:足侧(37.5%)、足背(50.0%)和其他部位(12.5%)。足侧和足背的中位缺损大小差异无统计学意义(P=0.069,Kruskal-Wallis 检验)。然而,在中位时间和中位绝对减少率方面差异有统计学意义(P<0.05,Kruskal-Wallis 检验)。本研究未发生严重并发症。总之,我们的研究结果表明,应用简单的皮肤拉伸系统和 NPWT 是治疗复杂糖尿病足创面的一种有效且安全的方法。然而,应更加注意适当的患者选择和术中判断,以确保伤口闭合并避免不必要的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6ea/8045371/332bab4bf97f/13018_2021_2405_Fig1_HTML.jpg

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