Møller Karina Lauenborg, Brauer Charlotte, Mikkelsen Sigurd, Loft Steffen, Simonsen Erik B, Koblauch Henrik, Bern Stine Hvid, Alkjær Tine, Hertel Ole, Becker Thomas, Larsen Karin Helweg, Bonde Jens Peter, Thygesen Lau Caspar
National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, Copenhagen, Denmark.
BMJ Open. 2017 May 6;7(5):e012651. doi: 10.1136/bmjopen-2016-012651.
Copenhagen Airport Cohort 1990-2012 presents a unique data source for studies of health effects of occupational exposure to air pollution (ultrafine particles) and manual baggage handling among airport employees. We describe the extent of information in the cohort and in the follow-up based on data linkage to the comprehensive Danish nationwide health registers. In the cohort, all information is linked to the personal identification number that also is used in Denmark Statistics demographic and socioeconomic databases and in the nationwide health registers.
The cohort covers 69 175 men in unskilled positions. The exposed cohort includes men in unskilled jobs employed at Copenhagen Airport in the period 1990-2012 either as baggage handlers or in other outdoor work. The reference cohort includes men in unskilled jobs working in the greater Copenhagen area.
The cohort includes environmental Global Positioning System (GPS) measurements in Copenhagen Airport, information on job function/task for each calendar year of employment between 1990 and 2012, exposure to air pollution at residence, average weight of baggage lifted per day and lifestyle. By linkage to registers, we retrieved socioeconomic and demographic data and data on healthcare contacts, drug subscriptions, incident cancer and mortality.
The size of the cohort and the completeness of the register-based follow-up allow a more accurate assessment of the possible health risks of occupational exposure to ultrafine particles and manual baggage handling at airports than in previous studies. We plan to follow the cohort for the incidence of ischaemic heart diseases, cerebrovascular disease, lung and bladder cancer, asthma and chronic obstructive pulmonary disease, and further for associations between heavy manual baggage handling and musculoskeletal disorders.
number 2012-41-0199.
哥本哈根机场队列研究（1990 - 2012年）为研究机场员工职业暴露于空气污染（超细颗粒物）及人工行李搬运对健康的影响提供了一个独特的数据源。我们基于与丹麦全国综合健康登记系统的数据链接，描述了该队列及随访中的信息范围。在这个队列中，所有信息都与个人识别号相关联，该识别号也用于丹麦统计局的人口统计和社会经济数据库以及全国健康登记系统。
该队列涵盖69175名从事非技术工作的男性。暴露队列包括1990年至2012年期间在哥本哈根机场从事非技术工作的男性，他们要么是行李搬运工，要么从事其他户外工作。参照队列包括在哥本哈根大区从事非技术工作的男性。
该队列包括哥本哈根机场的环境全球定位系统（GPS）测量数据、1990年至2012年各就业日历年的工作职能/任务信息、居住地的空气污染暴露情况、每日搬运行李的平均重量以及生活方式。通过与登记系统的链接，我们获取了社会经济和人口数据以及医疗接触、药物处方、癌症发病和死亡率数据。
与以往研究相比，该队列的规模以及基于登记系统的随访完整性使得能够更准确地评估机场职业暴露于超细颗粒物和人工行李搬运可能带来的健康风险。我们计划对该队列进行随访，以了解缺血性心脏病、脑血管疾病、肺癌和膀胱癌、哮喘以及慢性阻塞性肺疾病的发病率，并进一步研究重度人工行李搬运与肌肉骨骼疾病之间的关联。
编号2012 - 41 - 0199。
