Behringer Michael, Jedlicka Diana, Mester Joachim
Institute of Training Science and Sport Informatics, German Sport University Cologne, Cologne, Germany -
Institute of Training Science and Sport Informatics, German Sport University Cologne, Cologne, Germany.
J Sports Med Phys Fitness. 2018 Jun;58(6):903-909. doi: 10.23736/S0022-4707.17.07261-9. Epub 2017 May 5.
Muscle enzymes are cleared from the extracellular space by the lymphatic system, while smaller proteins enter the bloodstream directly. We investigated if manual lymphatic drainage (MLD), local cryotherapy (CRY), and rest (RST) differently affect the time course of creatine kinase (CK, 84 kDa) and heart-type fatty acid binding protein (h-FABP, 15 kDa) in the blood.
Randomized controlled trial. After 4x20 unilateral, eccentric accentuated knee extensions (with one-third of the maximal isometric force) 30 sports students randomly received either a 30 min MLD, CRY or they rested (RST) for the same amount of time. CK, h-FABP, neutrophil granulocytes, and the perceived muscle soreness were assessed before, immediately after, and 1 hour, 4 hours, and 24 hours after the exercise.
All measures increased significantly (P<0.001) after the protocol indicating that muscle damage was induced. However, the responses did not differ between the treatments.
Large and small damage markers were not affected differently by MLD, CRY, or RST, when applied for 30 min and no beneficial effects on inflammation or muscle soreness could be found for MLD and CRY when compared to RST. This information is particularly important for those sports physicians and conditioning specialists who use biochemical muscle damage markers to adjust the training load and volume of athletes.
肌肉酶通过淋巴系统从细胞外间隙清除，而较小的蛋白质则直接进入血液。我们研究了手法淋巴引流（MLD）、局部冷冻疗法（CRY）和休息（RST）是否对血液中肌酸激酶（CK，84 kDa）和心脏型脂肪酸结合蛋白（h-FABP，15 kDa）的时间进程有不同影响。
随机对照试验。30名体育专业学生进行4组每组20次的单侧离心加重膝关节伸展（使用最大等长力量的三分之一）后，随机接受30分钟的MLD、CRY治疗或相同时间的休息（RST）。在运动前、运动后即刻、运动后1小时、4小时和24小时评估CK、h-FABP、中性粒细胞以及肌肉酸痛感。
方案实施后所有指标均显著升高（P<0.001），表明诱导了肌肉损伤。然而，各治疗组之间的反应没有差异。
当应用30分钟时，大小损伤标志物受MLD、CRY或RST的影响并无差异，与RST相比，未发现MLD和CRY对炎症或肌肉酸痛有有益作用。这一信息对于那些使用生化肌肉损伤标志物来调整运动员训练负荷和运动量的运动医生和体能训练专家尤为重要。
