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神经外科医生使用抗癫痫药物实用指南

A practical guide to the use of anti-epileptic drugs by neurosurgeons.

作者信息

Afshari Fardad T, Michael Sophia, Ughratdar Ismail, Samarasekera Shanika

机构信息

a Department of Neurosurgery , University Hospitals Birmingham , Birmingham , UK.

b Department of Neurology , University Hospitals Birmingham , Birmingham , UK.

出版信息

Br J Neurosurg. 2017 Oct;31(5):551-556. doi: 10.1080/02688697.2017.1324618. Epub 2017 May 8.

Abstract

Initiation of anti-epileptic drugs is increasingly relevant to daily neurosurgical practice. Intracranial pathologies ranging from brain tumours to subarachnoid haemorrhage and traumatic brain injury are commonly associated with the subsequent development of seizures. The scope and range of anti-epileptic drugs available has increased dramatically in recent years and understanding the evidence base behind this class of drugs in addition to their interaction/side effect profiles is essential. In this review we aim to generate a practical guide for neurosurgeons regarding the use of different anti-epileptic medications in common neurosurgical conditions, including considerations for their use in pregnancy.

摘要

抗癫痫药物的起始使用在日常神经外科实践中变得越来越重要。从脑肿瘤到蛛网膜下腔出血和创伤性脑损伤等颅内病变通常与随后癫痫发作的发生有关。近年来,可用的抗癫痫药物的范围和种类大幅增加,了解这类药物背后的证据基础以及它们的相互作用/副作用情况至关重要。在本综述中,我们旨在为神经外科医生提供一份实用指南,内容涉及在常见神经外科疾病中使用不同抗癫痫药物的相关问题,包括在妊娠期间使用这些药物的注意事项。

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