Muazim Khazima, Hussain Zakir
School of Chemical and Materials Engineering (SCME), National University of Sciences & Technology (NUST), Sector H-12, 44000 Islamabad, Pakistan.
Mater Sci Eng C Mater Biol Appl. 2017 Jul 1;76:1274-1288. doi: 10.1016/j.msec.2017.02.121. Epub 2017 Feb 27.
Due to the abundance of its utilization in various applications, ranging from electronics to biomedicine, recent data witnessed manifold increase in the commercial potential of graphene oxide based biomaterials. Major contribution of such increased potential comes from the work on graphene oxide which carries unparalleled advantage over graphene itself and/or reduced graphene oxide. Few reviews have been published in previous years which have highlighted the capacity of graphene oxide in drug delivery and photothermal therapy application. But this review exclusively provides an outlook for the role of graphene oxide based magnetic composites in constituting a theranostic system through previously inaccessible options. These composites have been exploited for their use in drug delivery applications, biosensing, bioimaging and phototherapy. This review discusses the potential challenges and advantages of using graphene oxide based magnetic nanocomposites systems to explore much needed length and breadth of theranostics, not fully elaborated so far.
由于氧化石墨烯基生物材料在从电子到生物医学等各种应用中的广泛使用，最近的数据表明其商业潜力呈多倍增长。这种潜力增加的主要贡献来自于对氧化石墨烯的研究，氧化石墨烯相对于石墨烯本身和/或还原氧化石墨烯具有无与伦比的优势。前几年发表的少数综述强调了氧化石墨烯在药物递送和光热治疗应用中的能力。但本综述专门通过以前无法获得的选项，展望了基于氧化石墨烯的磁性复合材料在构建治疗诊断系统中的作用。这些复合材料已被用于药物递送应用、生物传感、生物成像和光疗。本综述讨论了使用基于氧化石墨烯的磁性纳米复合材料系统探索治疗诊断学急需的广度和深度时可能面临的挑战和优势，而这一点迄今为止尚未得到充分阐述。
