Nwebube Chineze, Glover Vivette, Stewart Lauren
Department of Psychology, Goldsmiths, University of London, 8 Lewisham Way, London, SE14 6NW, UK.
Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.
BMC Complement Altern Med. 2017 May 8;17(1):256. doi: 10.1186/s12906-017-1759-3.
Prenatal anxiety and depression are distressing for the expectant mother and can have adverse effects on her fetus and subsequently, her child. This study aimed to determine whether listening to specially composed songs would be an effective intervention for reducing symptoms of prenatal anxiety and depression.
Pregnant women were recruited online and randomly assigned to one of two groups: the music group (daily listening to specially composed songs) or control group (daily relaxation) for 12 weeks each. Self-report questionnaires were used to assess symptoms of State and Trait anxiety (Spielberger) and depression (Edinburgh Postnatal Depression Scale (EPDS)). Trait anxiety was measured as the primary outcome, while State anxiety and depression were the secondary outcomes. 111 participants were randomised to each group. 20 participants in the intervention group and 16 participants in the active control group completed the study.
The music group demonstrated lower Trait Anxiety (p = .0001) (effect size 0.80), State Anxiety (p = .02) (effect size 0.64), and EPDS (p = .002) (effect size 0.92) scores at week 12 compared to baseline, by paired t test. There were no such changes in the control group.
Though this pilot study had high levels of attrition, the results do suggest that regular listening to relaxing music should be explored further as an effective non-pharmacological means for reducing prenatal anxiety and depression.
ClinicalTrials.gov NCT02776293 LV-001. Registered 17 May 2016. Retrospectively registered.
产前焦虑和抑郁会令准妈妈痛苦不堪,且会对其胎儿乃至后续的孩子产生不良影响。本研究旨在确定聆听专门创作的歌曲是否为减轻产前焦虑和抑郁症状的有效干预措施。
通过网络招募孕妇,并将她们随机分为两组:音乐组(每天聆听专门创作的歌曲)或对照组(每天进行放松活动),每组为期12周。使用自我报告问卷评估状态焦虑和特质焦虑(斯皮尔伯格量表)以及抑郁症状(爱丁堡产后抑郁量表(EPDS))。将特质焦虑作为主要结局指标,状态焦虑和抑郁作为次要结局指标。每组随机分配111名参与者。干预组有20名参与者,积极对照组有16名参与者完成了研究。
通过配对t检验,与基线相比,音乐组在第12周时特质焦虑(p = 0.0001)(效应量0.80)、状态焦虑(p = 0.02)(效应量0.64)和EPDS(p = 0.002)(效应量0.92)得分更低。对照组则无此类变化。
尽管这项初步研究的失访率较高,但结果确实表明,定期聆听舒缓音乐作为一种减轻产前焦虑和抑郁的有效非药物手段,值得进一步探索。
ClinicalTrials.gov NCT02776293 LV - 001。于2016年5月17日注册。回顾性注册。