Department of Neuroscience and Experimental Psychology,University of Manchester,Manchester Academic Health Sciences Centre,UK.
Int Psychogeriatr. 2017 Jun;29(6):879-881. doi: 10.1017/S1041610217000370.
For the many clinicians au fait with the history of the clinical description of Parkinson's disease, they will be aware that the very earliest description of James Parkinson's "Shaking Palsy" in 1817 explicitly excluded the involvement of cognitive and emotional processes as manifestations of the disease. Within a short time following his treatise, it became all too clear to those in the field that Parkinson's disease is more than just a motor disorder, and as was aptly conceptualized by Paul McHugh, Professor of Psychiatry at Johns Hopkins Hospital from 1975 until 2001, Parkinson's disease is closer to being a "triadic disorder," encompassing motor, cognitive, and psychiatric elements (McHugh, 1989). Even this notion is now outdated, with the triad being accompanied by autonomic, pain, and other non-motor syndromes.
对于许多熟悉帕金森病临床描述历史的临床医生来说,他们会意识到,早在 1817 年,詹姆斯·帕金森(James Parkinson)对“震颤麻痹”的最早描述就明确排除了认知和情感过程作为疾病表现的参与。在他的论文发表后不久,该领域的人们就清楚地意识到,帕金森病不仅仅是一种运动障碍,正如约翰霍普金斯医院精神病学教授保罗·麦克休(Paul McHugh)在 1975 年至 2001 年期间所恰当设想的那样,帕金森病更接近一种“三联症”,包括运动、认知和精神方面的元素(McHugh,1989)。即使是这个概念现在也已经过时了,三联症伴随着自主神经、疼痛和其他非运动综合征。