比利时牛群中与牛疱疹病毒4型（BHV4）相关的疾病：对两个问题牛群的研究
BHV4 (bovine herpes virus 4) related disorders in Belgian cattle: a study of two problem herds.
作者信息
van Opdenbosch E, Wellemans G, Ooms L A, Degryse A D
机构信息
National Institute for Veterinary Research, Brussels, Belgium.
出版信息
Vet Res Commun. 1988;12(4-5):347-53. doi: 10.1007/BF00343255.
Two cattle farms, with a ten year history of BHV4 related postpartum metritis accompanied by fertility problems, were monitored during the winter season 1985-1986. BHV4 was isolated from the lochia from 55% of the animals on farm A and 66% of those on farm B. Respectively 59% and 30% of the animals presented postpartum metritis. In some animals virus multiplication was followed by severe leucopenia lasting several weeks. Indirect immunofluorescence (IIF) BHV4 seropositive as well as IIF seronegative animals were affected. The latter responded with a rapid or late IIF antibody reaction. No BHV4 seroneutralizing antibodies could be detected. The authors also suggest a possible role of BHV4 in the respiratory problems observed during the study.
1985 - 1986年冬季，对两个有十年与BHV4相关的产后子宫炎病史并伴有繁殖问题的养牛场进行了监测。从A农场55%的动物和B农场66%的动物的恶露中分离出了BHV4。分别有59%和30%的动物出现产后子宫炎。在一些动物中，病毒繁殖后出现了持续数周的严重白细胞减少症。间接免疫荧光法（IIF）检测显示，BHV4血清阳性和血清阴性的动物均受到影响。后者出现了快速或延迟的IIF抗体反应。未检测到BHV4血清中和抗体。作者还提出BHV4在研究期间观察到的呼吸道问题中可能起作用。
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