Schulz André, van Dyck Zoé, Lutz Annika P C, Rost Silke, Vögele Claus
Clinical Psychophysiology Laboratory, Institute for Health and Behaviour, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Clinical Psychophysiology Laboratory, Institute for Health and Behaviour, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Biol Psychol. 2017 Jul;127:25-33. doi: 10.1016/j.biopsycho.2017.05.004. Epub 2017 May 5.
Previous assessment methods of gastric interoception either rely on self-reports, or imply invasive procedures. We investigated the reliability of startle methodology as a non-invasive alternative for the assessment of afferent gastric signals. Twenty-four participants were tested on three separate days, on which they were requested to ingest water (either 0, 300 or 600ml), after 8h of fasting. On each assessment day, eye blink responses (EMG) to 10 acoustic startle stimuli (105dB) were assessed at 4 measurement points (before, 0, 7, 14min. after ingestion). Increased normogastric responses (EGG), ratings of satiety and fullness, and higher heart rate variability (RMSSD) suggested effective non-invasive induction of gastric distention. Startle responses were lower directly after ingestion of 600ml as compared to earlier and later measurements. These results suggest that startle methodology provides a reliable method to investigate afferent gastric signals. It could be useful to study possible dissociations between subjective reports and objective afferent gastric signals in eating or somatoform disorders.
以往评估胃内感受的方法要么依赖自我报告，要么涉及侵入性操作。我们研究了惊吓反射方法作为评估传入性胃信号的一种非侵入性替代方法的可靠性。24名参与者在三个不同的日子接受测试，要求他们在禁食8小时后摄入水（0、300或600毫升）。在每个评估日，在4个测量点（摄入前、摄入后0、7、14分钟）评估对10次听觉惊吓刺激（105分贝）的眨眼反应（肌电图）。正常胃电反应（EGG）增强、饱腹感和饱足感评分增加以及更高的心率变异性（RMSSD）表明胃扩张的有效非侵入性诱导。与早期和后期测量相比，摄入600毫升水后直接测得的惊吓反应较低。这些结果表明，惊吓反射方法为研究传入性胃信号提供了一种可靠的方法。这对于研究饮食或躯体形式障碍中主观报告与客观传入性胃信号之间可能存在的分离可能是有用的。
