Chang A E, Schaner E G, Conkle D M, Flye M W, Doppman J L, Rosenberg S A
Cancer. 1979 Mar;43(3):913-6. doi: 10.1002/1097-0142(197903)43:3<913::aid-cncr2820430319>3.0.co;2-q.
Conventional linear x-ray tomography is often used to search for pulmonary metastases but tends to underestimate extent of disease when compared with operative findings. In a prospective study, operative findings were correlated with computed axial tomography and conventional linear tomography performed on 25 patients with a history of extrathoracic malignancy and pulmonary nodules. Computed tomography detected 69 nodules of which 31 proved to be metastases. Conventional linear tomography detected 38 nodules of which 25 were metastases. Of the 54 resected nodules measuring greater than 3 mm, computed tomography detected 42; whereas conventional tomography detected 32. Only six of the 31 additional nodules (20%) detected by computed tomography and not by conventional tomography proved to be metastases. These results suggest that computed tomography is more sensitive than conventional tomography in detecting small pulmonary nodules; however, there is diminished specificity in identifying metastatic nodules.
传统的线性X线断层摄影术常用于寻找肺转移瘤，但与手术结果相比，往往会低估疾病的范围。在一项前瞻性研究中，对25例有胸外恶性肿瘤病史和肺结节的患者进行了手术结果与计算机断层扫描（CT）及传统线性断层摄影术的相关性研究。CT检测到69个结节，其中31个被证实为转移瘤。传统线性断层摄影术检测到38个结节，其中25个为转移瘤。在54个直径大于3mm的切除结节中，CT检测到42个；而传统断层摄影术检测到32个。CT检测到而传统断层摄影术未检测到的31个额外结节中，只有6个（20%）被证实为转移瘤。这些结果表明，CT在检测小肺结节方面比传统断层摄影术更敏感；然而，在识别转移瘤结节方面特异性降低。
