Sehic Adnan, Julardzija Fuad, Vegar-Zubovic Sandra, Sefic-Pasic Irmina
Radiology clinic, University Clinical Center of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Acta Inform Med. 2017 Mar;25(1):24-27. doi: 10.5455/aim.2017.25.24-27.
The aim of this study is to prove the advantages of combined use of T2 weighted three dimensional (T2 W 3D) and T1 weighted three dimensional contrast medium enhanced (T1 W 3D CE) magnetic resonance (MR) urography in displaying urinary tract in child population.
Total of 120 patients were included in the study, 71 (59%) male patients and 49 (41%) female patients. The study was conducted on the Radiology clinic, University of Sarajevo Clinical Center, during the period from February to November 2016. Patients were examined on the 1.5T and 3T MRI, with standard protocol which includes T2 W 3D and T1 W 3D contrast medium enhanced MR urography. In the post procesing quantitative measurement of signal intensity and evaluation of the display quality in the area of renal pelvis, middle of ureter and the mouth of the ureter were done. Measurement was concluded on Syngo software B13.
Analyzing the acquired data and statistically processing them we got results which have shown higher signal intensity of measured structures on T1 W 3D contrast medium enhanced MR urography on the level p<0.01 and p<0.05 compared to T2 W 3D MR urography in patients that had normal dynamics of contrast medium secretion. However, in kidneys with decreased function, T2 W 3D MR urography provided higher signal intensity and better display compared to T1 W 3D contrast medium enhanced MR urography on the level p<0.05 and p<0.01.
T2 W3D MR urography is useful in imaging nonfunctional kidney as well as in patients prone to allergic reactions, where as T1 W3D CE MR urography is at an advantage over T2 W 3D MR urography in imaging the kidney functionality, kidney dynamics measurement, it provides higher MRI signal intensity required for clear 3D reconstructions.
本研究旨在证明联合使用T2加权三维（T2W 3D）和T1加权三维对比剂增强（T1W 3D CE）磁共振（MR）尿路造影在显示儿童尿路方面的优势。
本研究共纳入120例患者，其中男性患者71例（59%），女性患者49例（41%）。该研究于2016年2月至11月在萨拉热窝大学临床中心放射科进行。患者接受1.5T和3T MRI检查，采用包括T2W 3D和T1W 3D对比剂增强MR尿路造影的标准方案。在后期处理中，对肾盂、输尿管中段和输尿管口区域的信号强度进行定量测量，并评估显示质量。测量在Syngo软件B13上完成。
对获取的数据进行分析并进行统计学处理后，我们得到的结果显示，与T2W 3D MR尿路造影相比，在对比剂分泌动力学正常的患者中，T1W 3D对比剂增强MR尿路造影上测量结构的信号强度在p<0.01和p<0.05水平更高。然而，在功能减退的肾脏中，与T1W 3D对比剂增强MR尿路造影相比，T2W 3D MR尿路造影在p<0.05和p<0.01水平提供了更高的信号强度和更好的显示效果。
T2W 3D MR尿路造影在对无功能肾以及易发生过敏反应的患者进行成像时很有用，而T1W 3D CE MR尿路造影在对肾脏功能、肾脏动力学测量进行成像方面优于T2W 3D MR尿路造影，它提供了清晰三维重建所需的更高MRI信号强度。
