Department of Materials Engineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Division of Science for Joint Reconstruction, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, 113-8655, Japan.
J Biomed Mater Res B Appl Biomater. 2018 Apr;106(3):1028-1037. doi: 10.1002/jbm.b.33918. Epub 2017 May 9.
Younger, active patients who undergo total hip arthroplasty (THA) have increasing needs for wider range of motion and improved stability of the joint. Therefore, bearing materials having not only higher wear resistance but also mechanical strength are required. Carbon fiber-reinforced poly(ether ether ketone) (CFR-PEEK) is known as a super engineering plastic that has great mechanical strength. In this study, we focused on poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-grafted CFR-PEEK and investigated the effects of PMPC grafting and the femoral heads materials on the wear properties of CFR-PEEK liners. Compared with untreated CFR-PEEK, the PMPC-grafted CFR-PEEK surface revealed higher wettability and lower friction properties under aqueous circumstances. In the hip simulator wear test, wear particles generated from the PMPC-grafted CFR-PEEK liners were fewer than those of the untreated CFR-PEEK liners. There were no significant differences in the size and the morphology of the wear particles between the differences of PMPC-grafting and the counter femoral heads. Zirconia-toughened alumina (ZTA) femoral heads had significantly smoother surfaces compared to cobalt-chromium-molybdenum alloy femoral heads after the hip simulator test. Thus, we conclude that the bearing combination of the PMPC-grafted CFR-PEEK liner and ZTA head is expected to be a lifelong bearing interface in THA. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1028-1037, 2018.
年轻、活跃的接受全髋关节置换术 (THA) 的患者对关节活动范围和稳定性的要求越来越高。因此,需要具有更高耐磨性和机械强度的轴承材料。碳纤维增强聚醚醚酮 (CFR-PEEK) 是一种已知的具有优异机械强度的超级工程塑料。在本研究中,我们专注于聚 (2-甲基丙烯酰氧乙基磷酸胆碱) (PMPC)-接枝 CFR-PEEK,并研究了 PMPC 接枝和股骨头材料对 CFR-PEEK 衬垫磨损性能的影响。与未处理的 CFR-PEEK 相比,PMPC 接枝 CFR-PEEK 表面在水相环境下表现出更高的润湿性和更低的摩擦性能。在髋关节模拟器磨损试验中,PMPC 接枝 CFR-PEEK 衬垫产生的磨损颗粒比未处理的 CFR-PEEK 衬垫少。PMPC 接枝和不同对股骨头之间的差异在磨损颗粒的大小和形态上没有显著差异。氧化锆增韧氧化铝 (ZTA) 股骨头在髋关节模拟器试验后表面明显比钴铬钼合金股骨头更光滑。因此,我们得出结论,PMPC 接枝 CFR-PEEK 衬垫和 ZTA 头的组合有望成为 THA 中的终身轴承界面。© 2017 Wiley Periodicals, Inc. J 生物材料研究杂志 B:应用生物材料,106B:1028-1037, 2018.