Bermudez-Rattoni F, Forthman D L, Sanchez M A, Perez J L, Garcia J
Instituto de Fisiologia Celular, Universidad Nacional Autónoma de México, Distrito.
Behav Neurosci. 1988 Oct;102(5):726-32. doi: 10.1037//0735-7044.102.5.726.
Conditioned flavor aversions (CFA) are acquired by anesthetized rats but effects of various anesthetics on acquisition of aversions for separate odor and taste components are unknown. In Experiment 1, rats drank tomato juice and then were tranquilized with "Innovar-Vet" or "Rompun" before receiving injections of lithium chloride. Neither drug interfered with acquisition of aversions. Innovar-Vet alone produced no aversions; Rompun alone produced mild aversions but did not enhance aversions when combined with lithium. In Experiments 2 and 3, rats received a compound odor/taste cue as they drank and then were anesthetized with pentobarbital before lithium injections. Anesthesia alone produced negligible aversions but facilitated taste-lithium aversions. During odor tests, odor aversions were weaker than taste aversions. These data extend previous work and suggest that CFA does not result from ordinary classical conditioning. A tripartite notation that unites CFA and classical conditioning is discussed.
条件性味觉厌恶（CFA）可在麻醉大鼠身上习得，但各种麻醉剂对单独气味和味道成分厌恶习得的影响尚不清楚。在实验1中，大鼠饮用番茄汁，然后在注射氯化锂之前用“Innovar-Vet”或“Rompun”使其镇静。两种药物均未干扰厌恶的习得。单独使用Innovar-Vet不会产生厌恶；单独使用Rompun会产生轻微厌恶，但与锂联合使用时不会增强厌恶。在实验2和3中，大鼠在饮用时接受复合气味/味道线索，然后在注射锂之前用戊巴比妥麻醉。单独麻醉产生的厌恶可忽略不计，但促进了味觉-锂厌恶。在气味测试期间，气味厌恶比味觉厌恶弱。这些数据扩展了先前的研究工作，并表明CFA并非源于普通的经典条件作用。讨论了一种将CFA和经典条件作用结合起来的三方表示法。
