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每日应用经颅直流电刺激(tDCS)8个月能否减缓阿尔茨海默病的认知衰退?一项病例研究。

Can 8 months of daily tDCS application slow the cognitive decline in Alzheimer's disease? A case study.

作者信息

Bystad Martin, Rasmussen Ingrid Daae, Grønli Ole, Aslaksen Per M

机构信息

a Department of Psychology, Research Group for Cognitive Neuroscience, Faculty of Health Sciences , University of Tromsø , Tromsø , Norway.

b Department of Geriatric Psychiatry , University Hospital of North Norway , Tromsø , Norway.

出版信息

Neurocase. 2017 Apr;23(2):146-148. doi: 10.1080/13554794.2017.1325911. Epub 2017 May 9.

Abstract

This case study presents a patient with early-onset Alzheimers disease, who applied transcranial direct current stimulation (tDCS) daily for 8 consecutive months. This was a much higher frequency than previous tDCS studies. Neuropsychological assessments were conducted before the first tDCS session, after 5 months and after 8 months. After 8 months, the patient's immediate recall improved with 39%, whereas delayed recall improved 23%. Overall, the results revealed that patient's cognitive functions were stabilized. There may be slight possibility that tDCS could slow the cognitive decline in Alzheimers disease. This should be investigated in clinical trials.

摘要

本病例研究展示了一位早发性阿尔茨海默病患者,该患者连续8个月每天接受经颅直流电刺激(tDCS)。这一频率比之前的tDCS研究高得多。在首次tDCS治疗前、5个月后和8个月后进行了神经心理学评估。8个月后,患者的即时回忆提高了39%,而延迟回忆提高了23%。总体而言,结果显示患者的认知功能得到了稳定。tDCS有可能轻微减缓阿尔茨海默病患者的认知衰退。这一点应在临床试验中进行研究。

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