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一名以癫痫发作作为大脑胶质瘤病症状的青少年。

An Adolescent Presenting With Seizures as a Symptom of Gliomatosis Cerebri.

作者信息

Blanco-Iglesias Elena, Cabeza Beatriz, Esparza Elena Garcia, de Prada Inmaculada, Lassaletta Alvaro, Budke Marcelo, Serrano Ana

机构信息

From the Pediatric Intensive Care Unit and.

Departments of Radiology.

出版信息

Pediatr Emerg Care. 2018 Dec;34(12):e229-e232. doi: 10.1097/PEC.0000000000001138.

Abstract

Gliomatosis cerebri is a diffuse infiltrating glioma of neuroepithelial origin that affects more than 2 cerebral lobes. This is rarely seen in pediatric patients. The clinical presentation and imaging are very unspecific, and a biopsy is typically needed for the diagnosis. Given the widespread nature of the disease, surgical treatment is not possible and has a poor overall prognosis. A pediatric patient presented with elevated intracranial pressure. All initial studies were negative, and the imaging showed a symmetrical affection involving the supratentorial and infratentorial regions. A biopsy ultimately confirmed gliomatosis cerebri. This case describes a unique clinical presentation of gliomatosis cerebri in a pediatric patient.

摘要

大脑胶质瘤病是一种起源于神经上皮的弥漫性浸润性胶质瘤,累及两个以上脑叶。这在儿科患者中很少见。临床表现和影像学表现非常不具特异性,通常需要活检来确诊。鉴于该疾病的广泛性,手术治疗不可行,总体预后较差。一名儿科患者出现颅内压升高。所有初始检查均为阴性,影像学显示幕上和幕下区域均有对称性受累。活检最终确诊为大脑胶质瘤病。本病例描述了一名儿科患者大脑胶质瘤病的独特临床表现。

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