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主动脉弓病变特征患者分支型胸主动脉腔内修复术的解剖学适宜性。

Anatomic Suitability for Branched Thoracic Endovascular Repair in Patients with Aortic Arch Pathological Features.

机构信息

Department of Surgery Amsterdam Cardiovascular Sciences Amsterdam University Medical Centres, Vrije Universiteit Amsterdam Amsterdam the Netherlands.

Department of Surgery Spaarne Gasthuis Haarlem the Netherlands.

出版信息

J Am Heart Assoc. 2020 Oct 20;9(20):e016695. doi: 10.1161/JAHA.120.016695. Epub 2020 Oct 3.

Abstract

Background Endovascular repair has become a viable alternative for aortic pathological features, including those located within the aortic arch. We investigated the anatomic suitability for branched thoracic endovascular repair in patients previously treated with conventional open surgery for aortic arch pathological features. Methods and Results Patients who underwent open surgery for aortic arch pathological features at our institution between 2000 and 2018 were included. Anatomic suitability was determined by strict compliance with the anatomic criteria within manufacturers' instructions for use for each of the following branched thoracic stent grafts: Relay Plus Double-Branched (Terumo-Aortic), TAG Thoracic Branch Endoprosthesis (W.L. Gore & Associates), Zenith Arch Branched Device (Cook-Medical), and Nexus Stent Graft System (Endospan Ltd/Jotec GmbH). Computed tomography angiography images were analyzed with outer luminal line measurements. A total of 377 patients (mean age, 64±14 years; 64% men) were identified, 153 of whom had suitable computed tomography angiography images for measurements. In total, 59 patients (15.6% of the total cohort and 38.6% of the measured cohort) were eligible for endovascular repair using at least one of the devices. Device suitability was 30.9% for thoracic aneurysms, 4.6% for type A dissections, 62.5% for type B dissections, and 28.6% for other pathological features. Conclusions The anatomic suitability for endovascular repair of all aortic arch pathological features was modest. The highest suitability rates were observed for thoracic aneurysms and for type B dissections, of which repair included part of the aortic arch. We suggest endovascular repair of arch pathological features should be reserved for high-volume centers with experience in endovascular arch repair.

摘要

背景

腔内修复已成为主动脉病变特征的一种可行替代方法,包括位于主动脉弓内的病变特征。我们研究了既往接受传统开放手术治疗主动脉弓病变特征的患者进行分支型胸主动脉腔内修复的解剖学适宜性。

方法和结果

本研究纳入了 2000 年至 2018 年期间在我院接受开放手术治疗主动脉弓病变特征的患者。解剖学适宜性通过严格遵循各制造商使用说明书中分支型胸主动脉覆膜支架的解剖学标准来确定,这些分支型胸主动脉覆膜支架包括 Relay Plus 双分叉型(泰尔茂-主动脉)、TAG 胸主动脉分支内支架(戈尔)、Zenith 弓状分支装置(库克医疗)和 Nexus 支架移植物系统(Endospan Ltd/Jotec GmbH)。采用外腔线测量法对 CT 血管造影图像进行分析。共纳入 377 例患者(平均年龄 64±14 岁,64%为男性),其中 153 例患者的 CT 血管造影图像可用于测量。共有 59 例患者(占总队列的 15.6%,可测量队列的 38.6%)至少有一种器械可用于血管内修复。胸主动脉瘤的器械适宜性为 30.9%,A型夹层为 4.6%,B 型夹层为 62.5%,其他病变特征为 28.6%。

结论

所有主动脉弓病变特征的血管内修复解剖学适宜性适中。胸主动脉瘤和 B 型夹层的修复包括部分主动脉弓,这两种疾病的器械适宜性最高。我们建议,应将弓部病变特征的血管内修复保留给在血管内弓部修复方面具有丰富经验的高容量中心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c8a/7763389/ecbb75b4f92f/JAH3-9-e016695-g001.jpg

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