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作者信息

Höhn René, Pfeiffer Norbert

出版信息

Klin Monbl Augenheilkd. 2017 Jul;234(7):931-948. doi: 10.1055/s-0043-106819. Epub 2017 May 9.

Abstract

Glaucoma is a heterogeneous group of diseases which all share retinal ganglion cell loss leading to a typical optic disc cupping and characteristic visual field defects. Glaucoma is the leading cause of irreversible blindness affecting 8.4 million people. In 2013, 65 million people suffered from glaucoma worldwide and the number will increase to about 112 million in 2040. This review provides an overview about the classification and genetic basics in glaucoma.

摘要

青光眼是一组异质性疾病，其共同特征是视网膜神经节细胞丧失，导致典型的视盘杯状凹陷和特征性视野缺损。青光眼是不可逆性失明的主要原因，影响着840万人。2013年，全球有6500万人患有青光眼，到2040年这一数字将增至约1.12亿人。本文综述了青光眼的分类及遗传学基础。