Walczak Krysia, Friendship Robert, Brockoff Egan, Greer Amy, Poljak Zvonimir
Department of Population Medicine, University of Guelph, Guelph, Ontario N1G 2W1 (Walczak, Friendship, Greer, Poljak); Prairie Swine Health, Red Deer, Alberta T4P 2T4 (Brockoff).
Can Vet J. 2017 May;58(5):472-481.
Treatment can be used as an indirect measure of morbidity, and treatment records can be used to describe disease patterns in a population. The aim of this study was to describe the rates of treatments with tiamulin and lincomycin by the intramuscular route in cohorts of pigs affected by swine dysentery. Data from treatment records from 19 cohorts of a 1500-head grower-finisher barn were analyzed using Poisson regression to determine factors associated with rates of treatment. Serial interval and reproductive numbers were extracted. Treatment rates displayed marked seasonality. The mean serial interval was estimated at 17 d with variability among batches. In the early period of most cohorts, the effective reproductive number did not exceed 1, and the highest estimate was 2.15 (95% CI: 1.46, 3.20). The average days-to-first treatment was 4.8 which suggests that pigs could have been infected at time of entry. The information about possible sources of infection and likely seasonality should be considered when developing disease and infection control measures in affected barns.
治疗可作为发病率的间接衡量指标,治疗记录可用于描述人群中的疾病模式。本研究的目的是描述受猪痢疾影响的猪群中通过肌肉注射途径使用泰妙菌素和林可霉素的治疗率。使用泊松回归分析了来自一个1500头生长育肥猪舍的19个猪群的治疗记录数据,以确定与治疗率相关的因素。提取了传播间隔和繁殖数。治疗率呈现出明显的季节性。估计平均传播间隔为17天,批次间存在差异。在大多数猪群的早期,有效繁殖数不超过1,最高估计值为2.15(95%置信区间:1.46,3.20)。首次治疗的平均天数为4.8天,这表明猪可能在进入时就已感染。在制定受影响猪舍的疾病和感染控制措施时,应考虑可能的感染源信息和可能的季节性。