Laboratory of Functional Nanostructures, Faculty of Chemistry, Adam Mickiewicz University in Poznań, Umultowska 89b, 61-614 Poznań, Poland.
Laboratory of Functional Nanostructures, Centre for Advanced Technologies, Adam Mickiewicz University, Umultowska 89c, 61-614 Poznań, Poland.
Nat Commun. 2017 May 10;8:15109. doi: 10.1038/ncomms15109.
Self-assembly of multiple building blocks via hydrogen bonds into well-defined nanoconstructs with selective binding function remains one of the foremost challenges in supramolecular chemistry. Here, we report the discovery of a enantiopure nanocapsule that is formed through the self-assembly of eight amino acid functionalised molecules in nonpolar solvents through 48 hydrogen bonds. The nanocapsule is remarkably robust, being stable at low and high temperatures, and in the presence of base, presumably due to the co-operative geometry of the hydrogen bonding motif. Thanks to small pore sizes, large internal cavity and sufficient dynamicity, the nanocapsule is able to recognize and encapsulate large aromatic guests such as fullerenes C and C. The structural and electronic complementary between the host and C leads to its preferential and selective binding from a mixture of C and C.
通过氢键将多种构建块自组装成具有选择性结合功能的明确定义的纳米结构仍然是超分子化学中最首要的挑战之一。在这里，我们报告了一种通过在非极性溶剂中通过 48 个氢键将 8 个氨基酸官能化分子自组装形成的对映纯纳米胶囊的发现。纳米胶囊非常坚固，在低温和高温以及存在碱的情况下都很稳定，这可能是由于氢键模体的协同几何形状。由于孔径小、内部空腔大且足够的动态性，纳米胶囊能够识别和封装大的芳香族客体，如富勒烯 C 和 C。主体和 C 之间的结构和电子互补性导致其优先和选择性地从 C 和 C 的混合物中结合。
