婴儿黑色素性神经外胚层肿瘤（MNTI）。1例病例的免疫组织化学和超微结构研究。
Melanotic neuroectodermal tumour of infancy (MNTI). Immunohistochemical and ultrastructural study of a case.
作者信息
Melissari M, Tragni G, Gaetti L, Gabrielli M, Bozzetti A, Raffaini M
机构信息
Dept. of Histopathology, University of Parma, Italy.
出版信息
J Craniomaxillofac Surg. 1988 Oct;16(7):330-6. doi: 10.1016/s1010-5182(88)80073-8.
A case of melanotic neuroectodermal tumour of infancy (MNTI) which occurred in the left lower jaw of a 15-months old child was studied by electron microscopy and immunohistochemical methods to verify the neural crest origin of this tumour. Two cell population were observed: pigment melanocyte-like cells and non-pigmented nerve-like cells. Immunohistochemical analysis with neuron-specific enolase (NSE) and S-100 protein visualized two cell subtypes in the non-pigmented cell population. The combined ultrastructural findings and immunohistochemical data confirm the neural crest origin of MNTI.
对一名15个月大儿童左下颌发生的婴儿黑色素性神经外胚层肿瘤（MNTI）病例进行了电子显微镜和免疫组织化学方法研究，以证实该肿瘤的神经嵴起源。观察到两种细胞群：色素性黑素细胞样细胞和无色素神经样细胞。用神经元特异性烯醇化酶（NSE）和S-100蛋白进行的免疫组织化学分析显示，在无色素细胞群中有两种细胞亚型。超微结构研究结果与免疫组织化学数据相结合，证实了MNTI的神经嵴起源。
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