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全球 168 个国家与糖相关的口腔疾病负担及相应的医疗保健费用。

Global Burden of Sugar-Related Dental Diseases in 168 Countries and Corresponding Health Care Costs.

机构信息

1 Martin Luther University Halle-Wittenberg, Institute for Agricultural and Nutritional Sciences, Halle (Saale), Germany.

2 Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD), Halle-Jena-Leipzig, Germany.

出版信息

J Dent Res. 2017 Jul;96(8):845-854. doi: 10.1177/0022034517708315. Epub 2017 May 10.

Abstract

Oral diseases such as dental caries, edentulism (tooth loss), periodontal disease (PD), and oral cancer currently constitute an increased major public health burden across the globe, with significant differences between countries. One of the main drivers of caries, edentulism, and PD is the excessive intake of sugars. Here, we aimed to quantify the global sugar-related dental health and cost burden in the year 2010. This study used a health-econometrical model to calculate the disease burden as well as the direct and indirect costs attributable to the intake of free sugars (mono- and disaccharides [MDS]). To this end, several databases from the Institute for Health Metrics and Evaluation (IHME), Organisation for Economic Co-operation and Development (OECD), Food and Agriculture Organization (FAO), and World Bank were used. In total, the corresponding disease burden in 168 countries and economic burden in 31 OECD countries were quantified. In 2010, the consumption of MDS was associated with a global dental disease burden of 4.1 million disability-adjusted life years (DALYs; 95% uncertainty interval [UI]: 2.1 to 7.4 million DALYs), with 2.7 million DALYs from MDS-related caries and 1.4 million DALYs from PD. In terms of economic costs, MDS-related dental diseases were associated with a global financial burden of 172 billion US dollars (USD; 95% UI: 91 to 295 billion USD), the largest share of which (151 billion USD) was incurred in OECD countries. Overall, 26.3% (95% UI: 13.3% to 47.5%) of the total global oral disease burden was attributed to the consumption of MDS. The present study emphasizes the need to further address the role of free sugars in oral health and nutrition policy. Although the largest share of the economic burden was accounted for by OECD countries, emerging economies should address this challenge early on in national public health policies if they are to avoid disease and the prospect of increased cost burdens.

摘要

口腔疾病,如龋齿、失牙(缺牙)、牙周病(PD)和口腔癌,目前在全球范围内构成了日益严重的主要公共卫生负担,各国之间存在显著差异。龋齿、失牙和 PD 的主要驱动因素之一是糖的过度摄入。在这里,我们旨在量化 2010 年全球与糖相关的口腔健康和成本负担。本研究使用健康计量经济学模型来计算与摄入游离糖(单糖和双糖[MDS])相关的疾病负担以及直接和间接成本。为此,使用了来自健康指标与评估研究所(IHME)、经济合作与发展组织(OECD)、联合国粮食及农业组织(FAO)和世界银行的几个数据库。总的来说,量化了 168 个国家的相应疾病负担和 31 个经合组织国家的经济负担。2010 年,MDS 的消耗与全球 410 万残疾调整生命年(DALY;95%不确定区间[UI]:210 万至 740 万 DALY)的口腔疾病负担相关,其中 270 万 DALY 来自 MDS 相关龋齿,140 万 DALY 来自 PD。就经济成本而言,MDS 相关的口腔疾病与全球 1720 亿美元(95%UI:910 亿至 2950 亿美元)的财务负担相关,其中最大份额(1510 亿美元)发生在经合组织国家。总体而言,26.3%(95%UI:13.3%至 47.5%)的全球口腔疾病总负担归因于 MDS 的消耗。本研究强调需要进一步解决游离糖在口腔健康和营养政策中的作用。尽管经济负担的最大份额由经合组织国家承担,但新兴经济体如果要避免疾病和增加成本负担的前景,就应在国家公共卫生政策中尽早应对这一挑战。

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