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影响配备医师的直升机紧急医疗服务中疼痛管理质量的因素

Factors Influencing Quality of Pain Management in a Physician Staffed Helicopter Emergency Medical Service.

作者信息

Oberholzer Nicole, Kaserer Alexander, Albrecht Roland, Seifert Burkhardt, Tissi Mario, Spahn Donat R, Maurer Konrad, Stein Philipp

机构信息

From the *Institute of Anesthesiology, University and University Hospital Zurich, Zurich, Switzerland; †Swiss Air-Ambulance, Rega (Rettungsflugwacht/Guarde Aérienne), Zurich, Switzerland; and ‡Department of Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.

出版信息

Anesth Analg. 2017 Jul;125(1):200-209. doi: 10.1213/ANE.0000000000002016.

Abstract

BACKGROUND

Pain is frequently encountered in the prehospital setting and needs to be treated quickly and sufficiently. However, incidences of insufficient analgesia after prehospital treatment by emergency medical services are reported to be as high as 43%. The purpose of this analysis was to identify modifiable factors in a specific emergency patient cohort that influence the pain suffered by patients when admitted to the hospital.

METHODS

For that purpose, this retrospective observational study included all patients with significant pain treated by a Swiss physician-staffed helicopter emergency service between April and October 2011 with the following characteristics to limit selection bias: Age > 15 years, numerical rating scale (NRS) for pain documented at the scene and at hospital admission, NRS > 3 at the scene, initial Glasgow coma scale > 12, and National Advisory Committee for Aeronautics score < VI. Univariate and multivariable logistic regression analyses were performed to evaluate patient and mission characteristics of helicopter emergency service associated with insufficient pain management.

RESULTS

A total of 778 patients were included in the analysis. Insufficient pain management (NRS > 3 at hospital admission) was identified in 298 patients (38%). Factors associated with insufficient pain management were higher National Advisory Committee for Aeronautics scores, high NRS at the scene, nontrauma patients, no analgesic administration, and treatment by a female physician. In 16% (128 patients), despite ongoing pain, no analgesics were administered. Factors associated with this untreated persisting pain were short time at the scene (below 10 minutes), secondary missions of helicopter emergency service, moderate pain at the scene, and nontrauma patients. Sufficient management of severe pain is significantly better if ketamine is combined with an opioid (65%), compared to a ketamine or opioid monotherapy (46%, P = .007).

CONCLUSIONS

In the studied specific Swiss cohort, nontrauma patients, patients on secondary missions, patients treated only for a short time at the scene before transport, patients who receive no analgesic, and treatment by a female physician may be risk factors for insufficient pain management. Patients suffering pain at the scene (NRS > 3) should receive an analgesic whenever possible. Patients with severe pain at the scene (NRS ≥ 8) may benefit from the combination of ketamine with an opioid. The finding about sex differences concerning analgesic administration is intriguing and possibly worthy of further study.

摘要

背景

疼痛在院前环境中经常出现,需要迅速且充分地进行治疗。然而,据报道,紧急医疗服务进行院前治疗后镇痛不足的发生率高达43%。本分析的目的是确定特定急诊患者队列中影响患者入院时疼痛程度的可改变因素。

方法

为此,这项回顾性观察研究纳入了2011年4月至10月间由瑞士配备医生的直升机紧急服务治疗的所有有明显疼痛的患者,具备以下特征以限制选择偏倚:年龄>15岁、现场和入院时记录的疼痛数字评分量表(NRS)、现场NRS>3、初始格拉斯哥昏迷量表>12以及国家航空咨询委员会评分<VI。进行单变量和多变量逻辑回归分析,以评估与疼痛管理不足相关的直升机紧急服务的患者和任务特征。

结果

共有778例患者纳入分析。298例患者(38%)被确定为疼痛管理不足(入院时NRS>3)。与疼痛管理不足相关的因素包括较高的国家航空咨询委员会评分、现场NRS高、非创伤患者、未给予镇痛药以及由女医生治疗。16%(128例患者)尽管仍有疼痛,但未给予镇痛药。与这种持续未治疗疼痛相关的因素包括在现场停留时间短(低于10分钟)、直升机紧急服务的二次任务、现场中度疼痛以及非创伤患者。与氯胺酮或阿片类药物单一疗法(46%,P = 0.007)相比,氯胺酮与阿片类药物联合使用时,严重疼痛的充分管理明显更好(65%)。

结论

在研究的特定瑞士队列中,非创伤患者、执行二次任务的患者、转运前在现场仅接受短时间治疗的患者、未接受镇痛药的患者以及由女医生治疗可能是疼痛管理不足的危险因素。现场疼痛的患者(NRS>3)应尽可能接受镇痛药治疗。现场严重疼痛的患者(NRS≥8)可能受益于氯胺酮与阿片类药物的联合使用。关于镇痛药给药的性别差异这一发现很有趣,可能值得进一步研究。

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