Huang Shucheng, Chen Li, Mao Yuping, Tong Hongwei
Department of Cardiothoracic Surgery Department of Pathology, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou, China.
Medicine (Baltimore). 2017 May;96(19):e6474. doi: 10.1097/MD.0000000000006474.
Primary extracranial meningiomas are rare outside the head and neck region.
A 44-year-old female patient had chest pain for more than 1 year.
Preoperative chest computed tomography (CT) scan revealed a nodule in the right lower lobe, 1.8 cm in diameter. Tumor tissues were examined by immunohistochemistry for vimentin and S-100.
Histopathologically, the tumor was characterized by whorled nests of spindle-shaped cells accompanied by psammoma bodies. Immunohistochemistry demonstrated tumor cell positivity for vimentin and S-100. This case was diagnosed as a primary pulmonary meningioma. The tumor was removed by a thoracoscopic pulmonary wedge resection.
Postoperative cranial and spinal CT scan did not show any intracranial or spinal mass. No recurrence of the tumor was reported at the time of writing up this case report.
A primary pulmonary meningioma should be considered in the differential diagnosis workup of pulmonary nodules.
原发性颅外脑膜瘤在头颈部区域以外较为罕见。
一名44岁女性患者胸痛超过1年。
术前胸部计算机断层扫描(CT)显示右肺下叶有一个直径1.8厘米的结节。对肿瘤组织进行波形蛋白和S-100免疫组织化学检查。
组织病理学上,肿瘤的特征是梭形细胞呈漩涡状巢状排列,并伴有砂粒体。免疫组织化学显示肿瘤细胞波形蛋白和S-100呈阳性。该病例被诊断为原发性肺脑膜瘤。通过胸腔镜肺楔形切除术切除肿瘤。
术后头颅和脊柱CT扫描未显示任何颅内或脊柱肿块。在撰写本病例报告时,未报告肿瘤复发。
在肺结节的鉴别诊断检查中应考虑原发性肺脑膜瘤。