Izumi Nobuhiro, Nishiyama Noritoshi, Iwata Takashi, Nagano Koshi, Tsukioka Takuma, Hanada Shoji, Suehiro Shigefumi
Department of Thoracic Surgery, Osaka City University Hospital, Osaka, Japan.
Ann Thorac Surg. 2009 Aug;88(2):647-8. doi: 10.1016/j.athoracsur.2008.12.058.
An 18-year-old woman presented with hemoptysis during long-distant running. A chest computed tomographic scan revealed a well-demarcated, round-shaped, solitary mass (3.0 cm in diameter) in the left pulmonary hilum. The bleeding was getting more often and a left upper lobectomy was carried out to avoid critical airway bleeding. A solid proliferation of short spindle cells with a remarkable whorl pattern was demonstrated histologically. Immunohistochemical studies showed positive for vimentin and S-100, and focally positive for epithelial membrane antigen. Primary pulmonary meningioma was thus diagnosed. The patient is well without recurrent disease 15 months after surgery.
一名18岁女性在长跑时出现咯血。胸部计算机断层扫描显示左肺门有一个边界清晰、圆形的孤立肿块（直径3.0厘米）。出血越来越频繁，遂进行了左上肺叶切除术以避免严重气道出血。组织学检查显示短梭形细胞呈实性增生，有明显的漩涡状结构。免疫组织化学研究显示波形蛋白和S-100呈阳性，上皮膜抗原局灶性阳性。由此诊断为原发性肺脑膜瘤。患者术后15个月情况良好，无疾病复发。
