Chow Ke Shuan, Beijerink Niek J, Ettinger Stephen, Fliegner Reuben, Beatty Julia A, Barrs Vanessa R
Valentine Charlton Cat Hospital, Department of Veterinary Science, The University of Sydney, Sydney, Australia.
The Evelyn Williams Visiting Professor, Department of Veterinary Science, The University of Sydney, Sydney, Australia.
JFMS Open Rep. 2015 Apr 28;1(1):2055116915579680. doi: 10.1177/2055116915579680. eCollection 2015 Jan-Jun.
A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger's syndrome). The cat was treated with sildenafil (0.25-0.6 mg/kg) for 10 months. There were no apparent treatment-related adverse effects. Improvement in clinical signs was noted, although increasing doses of sildenafil were required. After 10 months the cat significantly deteriorated and was euthanased.
一只2岁已绝育的暹罗猫出现虚弱和呼吸困难症状，被诊断患有房间隔缺损和肺动脉高压，导致右向左分流（艾森曼格综合征）。该猫接受了10个月的西地那非治疗（0.25 - 0.6毫克/千克）。未发现明显的与治疗相关的不良反应。尽管需要增加西地那非剂量，但临床症状有改善。10个月后，猫的病情显著恶化，最终实施了安乐死。
