Pimenta Paulo, Alves-Pimenta Sofia, Barros João, Pereira Maria J, Maltez Luís, Maduro A Paula, Cardoso Luís, Coelho Ana C
Hospital Veterinário de Trás-os-Montes, Vila Real, Portugal.
Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Trás-os-Montes e Alto Douro, Vila Real, Portugal.
JFMS Open Rep. 2015 Jul 6;1(2):2055116915593963. doi: 10.1177/2055116915593963. eCollection 2015 Jul-Dec.
We report a clinical case of blepharitis due to yeasts in a 2-year-old stray cat from northern Portugal (Vila Real) without concurrent naso-ocular signs. Ophthalmological examination revealed mucopurulent discharge from an open wound in the right upper and lower lids. Slit-lamp biomicroscopy showed a normal anterior segment, and intraocular pressure was within the normal reference interval. No fundoscopic alterations were detected in either eye by direct and indirect ophthalmoscopic examination. Cytological examination of an appositional smear showed numerous polymorphic neutrophils and macrophages, together with spherical yeast cells compatible with species. Molecular analysis by means of PCR and restriction fragment length polymorphism identified genotype VNI. The cat was treated with itraconazole, and amoxicillin and clavulanic acid, combined with a commercial ear ointment and an imidacloprid/moxidectin spot-on application for bilateral parasitic otitis caused by . One month after treatment, the clinical signs were completely resolved. Localised cutaneous lesions, as in the present case, probably result from contamination of cat-scratch injuries with viable encapsulated yeasts. This is, to the best of our knowledge, the first clinical report of feline blepharitis due to without concurrent naso-ocular signs. The current findings, together with those from recent reports of the infection in domestic animals, should alert the veterinary community both in Portugal and in Europe to this underdiagnosed disease.
我们报告了一例来自葡萄牙北部（维拉雷亚尔）的2岁流浪猫因酵母菌引起睑缘炎的临床病例，该猫无并发鼻眼症状。眼科检查发现右上睑和下睑开放性伤口有黏液脓性分泌物。裂隙灯生物显微镜检查显示眼前节正常，眼压在正常参考区间内。直接和间接检眼镜检查均未发现任何一只眼睛有眼底改变。对贴壁涂片进行细胞学检查发现大量多形核中性粒细胞和巨噬细胞，以及与该菌种相符的球形酵母细胞。通过聚合酶链反应（PCR）和限制性片段长度多态性进行分子分析，鉴定出基因型VNI。该猫接受了伊曲康唑、阿莫西林和克拉维酸治疗，并结合一种商业耳部软膏以及用于治疗由 引起的双侧寄生性中耳炎的吡虫啉/莫昔克丁点滴剂。治疗一个月后，临床症状完全消失。如本病例中的局限性皮肤病变，可能是由猫抓伤口被活的包膜酵母菌污染所致。据我们所知，这是首例无并发鼻眼症状的猫因 引起睑缘炎的临床报告。目前的研究结果，连同最近关于家畜感染的报告结果，应提醒葡萄牙和欧洲的兽医界注意这种诊断不足的疾病。
