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基于铁电陶瓷/聚合物复合材料的电容式电极阵列用于体内记录。

A Ferroelectric Ceramic/Polymer Composite-Based Capacitive Electrode Array for In Vivo Recordings.

机构信息

State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China (UESTC), Chengdu, Sichuan, 610054, P. R. China.

Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China (UESTC), Chengdu, Sichuan, 610054, P. R. China.

出版信息

Adv Healthc Mater. 2017 Aug;6(16). doi: 10.1002/adhm.201700305. Epub 2017 May 11.

Abstract

A new implantable capacitive electrode array for electrocorticography signal recording is developed with ferroelectric ceramic/polymer composite. This ultrathin and electrically safe capacitive electrode array is capable of attaching to the biological tissue conformably. The barium titanate/polyimide (BaTiO /PI) nanocomposite with high dielectric constant is successfully synthesized and employed as the ultrathin dielectric layer of the capacitive BaTiO /PI electrode array. The performance of the capacitive BaTiO /PI electrode array is evaluated by electrical characterization and 3D finite-element modeling. In vivo, neural experiments on the visual cortex of rats show the reliability of the capacitive BaTiO /PI electrode array. This work shows the potentials of capacitive BaTiO /PI electrode array in the field of brain/computer interfaces.

摘要

一种新型的可植入式电容式电极阵列,用于脑电信号记录,采用铁电陶瓷/聚合物复合材料制成。这种超薄且电安全的电容式电极阵列能够贴合生物组织。成功合成了具有高介电常数的钛酸钡/聚酰亚胺(BaTiO 3 /PI)纳米复合材料,并将其用作电容式 BaTiO 3 /PI 电极阵列的超薄介电层。通过电特性和三维有限元建模对电容式 BaTiO 3 /PI 电极阵列的性能进行了评估。在体内,大鼠视觉皮层的神经实验表明了电容式 BaTiO 3 /PI 电极阵列的可靠性。这项工作展示了电容式 BaTiO 3 /PI 电极阵列在脑机接口领域的潜力。

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