Nan Y M
Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang 050051, China.
Zhonghua Gan Zang Bing Za Zhi. 2017 Apr 20;25(4):241-245. doi: 10.3760/cma.j.issn.1007-3418.2017.04.001.
Liver cirrhosis is the severe period of chronic liver diseases, especially decompensated liver cirrhosis and its complications, such as ascites, esophagogastric variceal bleeding, hepatic encephalopathy, acute kidney injury, and hepatocellular carcinoma, which greatly affect patients' quality of life and even threaten their lives. Early prevention and treatment of the causes of development and progression and pathogenic mechanism may slow down or reverse liver cirrhosis and its severe complications. Once the disease progresses to portal hypertension and related complications, it is very important to select preventive measures for acute exacerbation of different complications, as well as the methods and timing for treatment in acute stage, which may help to save patients' lives and improve their prognosis.
肝硬化是慢性肝病的严重阶段，尤其是失代偿期肝硬化及其并发症，如腹水、食管胃静脉曲张出血、肝性脑病、急性肾损伤和肝细胞癌，这些极大地影响患者的生活质量，甚至威胁其生命。早期预防和治疗疾病发展、进展的原因及发病机制可能会减缓或逆转肝硬化及其严重并发症。一旦疾病进展至门静脉高压及相关并发症，选择针对不同并发症急性加重的预防措施以及急性期的治疗方法和时机非常重要，这可能有助于挽救患者生命并改善其预后。
