成釉细胞瘤的染色体组型分析和DNA流式细胞术
Karyotyping and DNA flow cytometry of an orchidoblastoma.
作者信息
Oosterhuis J W, Castedo S M, de Jong B, Seruca R, Buist J, Schraffordt Koops H, Leeuw J B
机构信息
Department of Pathology, State University of Groningen, The Netherlands.
出版信息
Cancer Genet Cytogenet. 1988 Nov;36(1):7-11. doi: 10.1016/0165-4608(88)90069-6.
PMID:2849502
Abstract
The first karyotype of an orchidoblastoma is described. The most striking finding is the absence of the i(12p) marker chromosome, considered specific for testicular germ cell tumors of adults. Differences between infantile and adult testicular germ cell tumors are discussed, as are features that infantile testicular germ cell tumors have in common with extragonadal germ cell tumors.
摘要
首次描述了兰花母细胞瘤的核型。最显著的发现是缺乏i(12p)标记染色体，该染色体被认为是成人睾丸生殖细胞肿瘤的特异性染色体。讨论了婴儿型和成人型睾丸生殖细胞肿瘤之间的差异，以及婴儿型睾丸生殖细胞肿瘤与性腺外生殖细胞肿瘤的共同特征。
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