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奶牛颗粒细胞和卵泡液中与年龄相关的变化。

Age-associated changes in granulosa cells and follicular fluid in cows.

作者信息

Iwata Hisataka

机构信息

Tokyo University of Agriculture, Kanagawa 243-0034, Japan.

出版信息

J Reprod Dev. 2017 Aug 19;63(4):339-345. doi: 10.1262/jrd.2017-048. Epub 2017 May 12.

DOI:10.1262/jrd.2017-048
PMID:28496019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5593084/
Abstract

Age-associated decline in oocyte quality is common in mammals. Oocytes take a long time to reach their full-grown size in large animals, and maternal physical conditions profoundly affect follicle development. Aging affects the oocyte itself as well as the surrounding environment, such as granulosa cells and follicular fluid. This review discusses age-associated changes that occur in granulosa cells and follicular fluid in cows and suggests that age-associated decline in granulosa cells and follicular fluid hampers proper oocyte development.

摘要

卵母细胞质量随年龄的下降在哺乳动物中很常见。在大型动物中，卵母细胞需要很长时间才能发育到完全成熟的大小，并且母体身体状况会深刻影响卵泡发育。衰老不仅会影响卵母细胞本身，还会影响其周围环境，如颗粒细胞和卵泡液。本文综述了奶牛颗粒细胞和卵泡液中发生的与年龄相关的变化，并表明颗粒细胞和卵泡液中与年龄相关的衰退会阻碍卵母细胞的正常发育。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/63440b74bca3/jrd-63-339-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/b446d6215787/jrd-63-339-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/368242211e16/jrd-63-339-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/a21221efde68/jrd-63-339-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/4857c6a9cf6f/jrd-63-339-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/63440b74bca3/jrd-63-339-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/b446d6215787/jrd-63-339-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/368242211e16/jrd-63-339-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/a21221efde68/jrd-63-339-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/4857c6a9cf6f/jrd-63-339-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af9/5593084/63440b74bca3/jrd-63-339-g005.jpg

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