Nishino Takeshi, Takizawa Hiromitsu, Nishioka Kohei, Fujimoto Keisuke, Miyamoto Naoki, Aoyama Mariko, Sawada Toru, Kawakita Naoya, Kajiura Koichiro, Toba Hiroaki, Kawakami Yukikiyo, Yoshida Mitsuteru
Department of Thoracic, Endocrine Surgery and Oncology, University of Tokushima Graduate School, Tokushima, Japan.
Kyobu Geka. 2017 May;70(5):393-396.
Malignant pleural mesothelioma sometimes accompanies intractable neumothorax due to the visceral pleural invasion of the tumor. A 68-years-old man was found to have massive pleural effusion and pleural mass combined with pneumothorax by computed tomography(CT). CT guided biopsy revealed the mass to be malignant pleural mesothelioma. Since continuous air leakage was observed by chest drainage, pleurodesis by OK-432 twice and bronchial occlusion by Endobronchial Watanabe Spigot (EWS)were performed. But air leakage continued, and the surgery was performed, however the treatment failed to stop the air leakage. Finally, the intrapleural administration of diluted fibrin glue was challenged and the air leakage stopped immediately after the treatment.
恶性胸膜间皮瘤有时会因肿瘤侵犯脏层胸膜而伴有难治性气胸。一名68岁男性经计算机断层扫描（CT）发现有大量胸腔积液、胸膜肿块合并气胸。CT引导下活检显示肿块为恶性胸膜间皮瘤。由于胸腔引流观察到持续漏气，遂行OK - 432胸膜固定术两次及经支气管渡边栓子（EWS）支气管封堵术。但漏气仍持续，遂进行手术，然而治疗未能阻止漏气。最后，尝试胸腔内注射稀释纤维蛋白胶，治疗后漏气立即停止。
