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埃塞俄比亚西南部吉马大学专科医院孕产妇死亡的趋势及原因:一项配对病例对照研究

Trends and causes of maternal mortality in Jimma University Specialized Hospital, southwest Ethiopia: a matched case-control study.

作者信息

Legesse Tegene, Abdulahi Misra, Dirar Anteneh

机构信息

Department of Public Health, Collage of Health Science, Mizan-Tepi University, Mizan Teferi, Ethiopia.

Department of Population and Family Health, College of Health Sciences, Jimma University, Jimma, Oromia Regional State, Ethiopia.

出版信息

Int J Womens Health. 2017 May 3;9:307-313. doi: 10.2147/IJWH.S123455. eCollection 2017.

Abstract

INTRODUCTION

Measures of maternal death are fundamental to a country's health and development status. In developing countries, it remains a daunting and largely unmet public health challenge. There were two studies completed over 10 years ago in Jimma University Specialized Hospital to identify trends, but recently there have been many changes in Ethiopia to reduce maternal death. Therefore, it is important to track the achievements made in Ethiopia in the context of Jimma University Specialized Hospital. No study undertaken in the country has quantified deaths of women from specific causes after controlling confounders.

OBJECTIVE

To assess trends and causes of maternal death in Jimma University Specialized Hospital, southwest Ethiopia.

METHODS

A time-matched case-control study was conducted on 600 (120 cases and 480 controls) females who utilized obstetrics and gynecology services from January 2010 to December 2014. To observe trends in maternal death, maternal mortality ratio was calculated for each year. Stata version 13 was used to analyze causal inference using propensity score matching method.

RESULTS

Maternal mortality ratio was 857/100,000 and had a decreasing trend from it's highest in 2010 of 1,873/100,000 to it's lowest of 350/100,000 in 2014. The leading cause of maternal death was hemorrhage (54%) (β=0.477, 95% confidence interval [CI]: 0.307, 0.647), followed by pregnancy-induced hypertension (20%) (β=0.232, 95% CI: 0.046, 0.419), and anemia (12%) (β=0.110, 95% CI: 0.017, 0.204).

CONCLUSION

There is a decreasing trend of maternal death. Hemorrhage was the major cause of death identified in each year of study.

摘要

引言

孕产妇死亡指标是衡量一个国家健康与发展状况的根本要素。在发展中国家,这仍是一项艰巨且远未得到解决的公共卫生挑战。10多年前在吉姆马大学专科医院完成了两项研究以确定相关趋势,但近来埃塞俄比亚为降低孕产妇死亡发生了诸多变化。因此,在吉姆马大学专科医院的背景下追踪埃塞俄比亚所取得的成就很重要。该国尚未有研究在控制混杂因素后对特定原因导致的女性死亡进行量化。

目的

评估埃塞俄比亚西南部吉姆马大学专科医院孕产妇死亡的趋势及原因。

方法

对2010年1月至2014年12月期间使用妇产科服务的600名女性(120例病例和480名对照)进行了时间匹配病例对照研究。为观察孕产妇死亡趋势,计算了每年的孕产妇死亡率。使用Stata 13版本通过倾向得分匹配法分析因果推断。

结果

孕产妇死亡率为857/10万,呈下降趋势,从2010年最高的1873/10万降至2014年最低的350/10万。孕产妇死亡的主要原因是出血(54%)(β=0.477,95%置信区间[CI]:0.307,0.647),其次是妊娠高血压(20%)(β=0.232,95%CI:0.046,0.419)和贫血(12%)(β=0.ll0,95%CI:0.017,0.204)。

结论

孕产妇死亡呈下降趋势。出血是研究各年份中确定的主要死因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc8f/5422567/747b08e82227/ijwh-9-307Fig1.jpg

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