Ferreira António M, Carmo Pedro, Adragão Pedro
Hospital Santa Cruz - Western Lisbon Hospital Centre, Lisbon, Portugal.
J Atr Fibrillation. 2012 Apr 14;4(6):435. doi: 10.4022/jafib.435. eCollection 2012 Apr-May.
Congestive heart failure (CHF) and atrial fibrillation (AF) are two increasingly common conditions that predispose to each other and frequently coexist. Cardiac resynchronization therapy(CRT) has emerged as an important therapeutic modality for selected patients with end-stage CHF. However, despite the high prevalence of AF in patients eligible for CRT, almost all the randomized clinical trials that validated the benefit of resynchronization therapy excluded patients with preexisting AF. In this review, we examine the available evidence on the benefits and limitations of CRT in patients with AF and discuss recent data that narrowed the knowledge gap on this topic.
充血性心力衰竭(CHF)和心房颤动(AF)是两种日益常见的疾病,它们相互影响且常常共存。心脏再同步治疗(CRT)已成为特定终末期CHF患者的重要治疗方式。然而,尽管符合CRT治疗条件的患者中AF患病率很高,但几乎所有证实再同步治疗益处的随机临床试验都排除了已患有AF的患者。在本综述中,我们研究了CRT治疗AF患者的益处和局限性的现有证据,并讨论了最近缩小该主题知识差距的数据。