心房颤动与静脉血栓栓塞——病理生理学、风险评估及CHADS-VASc评分
AF and Venous Thromboembolism - Pathophysiology, Risk Assessment and CHADS-VASc score.
作者信息
Shariff Nasir, Aleem Abdul, Singh Mukesh, Z Li Yuan, J Smith Stacey
机构信息
Department of Cardiovascular Medicine, Lehigh Valley Health Network, Pennsylvania, USA.
Sri Siddhartha Medical College, Karnataka, India.
出版信息
J Atr Fibrillation. 2012 Oct 6;5(3):649. doi: 10.4022/jafib.649. eCollection 2012 Oct-Nov.
Abstract
Atrial fibrillation (AF) and venous thromboembolism (VTE) are the two most common medical conditions managed with anti-coagulation therapy. Not all the patients with decreased mobility or AF have a similar risk for thromboembolism. The risk factors for venous thromboembolism and thromboembolism associated with AF are described in various studies. Considering that the two conditions have similar pathophysiologic basis of clot formation, one could imply that the risk factors for the occurrence of thrombosis could be similar. The present review focuses on the similarities and differences in the clinical risk factors of VTE and AF related thromboembolism. We will also be discussing the role of CHADS-VASc scoring system in the risk assessment of VTE.
摘要
心房颤动（AF）和静脉血栓栓塞症（VTE）是接受抗凝治疗的两种最常见的病症。并非所有行动不便或患有房颤的患者发生血栓栓塞的风险都相似。关于静脉血栓栓塞症以及与房颤相关的血栓栓塞症的风险因素，已有多项研究进行了描述。鉴于这两种病症在血栓形成方面具有相似的病理生理基础，有人可能会认为血栓形成的风险因素可能相似。本综述重点关注VTE和房颤相关血栓栓塞症临床风险因素的异同。我们还将讨论CHADS-VASc评分系统在VTE风险评估中的作用。
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