Khoury Ziad El, Bhakta Deepak
Krannert Institute of Cardiology, Indiana University School of Medicine, Indiana University Health Physicians.
J Atr Fibrillation. 2013 Feb 12;5(5):594. doi: 10.4022/jafib.594. eCollection 2013 Feb-Mar.
Atrial fibrillation (AF) is a common disorder associated with significant morbidities and presents several challenges for the control of symptoms and prevention of long-term implications. Atrial defibrillators (ADs), used for rhythm control in patients with symptoms refractory to medical therapy, can detect recurrences of the arrhythmia, allow prompt patient-directed treatment, and have the potential to reduce hospitalizations and improve quality of life. The efficacy of this form of therapy is highest in patients with paroxysmal AF, and with the use of a coronary sinus shocking lead. While R-wave synchronized shocks are a prerequisite for a safe use, the procedure is well tolerated and usually not associated with long-term psychological side effects. Limitations of ADs include acute and chronic complications related to cardiac rhythm device implantation, the requirement in some cases for more than one shock to terminate AF, the discomfort from shocks, as well as the need for sedation to alleviate pain from the shocks. With the ever-expanding role of catheter-based therapies for AF, it seems that the role of ADs in this regard is rather limited.
心房颤动(AF)是一种常见疾病,伴有严重的发病率,在症状控制和预防长期影响方面面临诸多挑战。心房除颤器(ADs)用于药物治疗难治性症状患者的节律控制,可检测心律失常的复发,实现及时的针对患者的治疗,并有可能减少住院次数和改善生活质量。这种治疗形式在阵发性房颤患者中疗效最高,且使用冠状静脉窦电击导线时效果更佳。虽然R波同步电击是安全使用的前提条件,但该操作耐受性良好,通常不会产生长期心理副作用。ADs的局限性包括与心脏节律装置植入相关的急性和慢性并发症、某些情况下需要多次电击才能终止房颤、电击带来的不适,以及需要镇静以减轻电击引起的疼痛。随着基于导管的房颤治疗作用不断扩大,ADs在这方面的作用似乎相当有限。