Adler Jeffrey, Colegrove Dustin J
Penn State University Milton S. Hershey College of Medicine Hershey, PA 17033.
J Atr Fibrillation. 2013 Jun 30;6(1):379. doi: 10.4022/jafib.379. eCollection 2013 Jun-Jul.
The development of thyrotoxicosis following the administration of iodinated contrast is a rare occurrence. The effect, referred to as the Jod-Basedow effect, is often observed in patients with underlying thyroid disease who develop thyrotoxicosis subsequent to the exposure of exogenous iodide. An example of an iatrogenic cause for this event may be seen when a large iodide load is given intravenously for studies or procedures. Thyrotoxicosis can also lead to cardiac arrhythmias including atrial fibrillation. This is a case presentation of a 74 year old female who developed thyrotoxicosis as well as new onset atrial fibrillation approximately one week after receiving iodinated contrast dye for a diagnostic CT of the abdomen. We further review the prior published literature in regard to atrial fibrillation and thyrotoxicosis.
使用碘化造影剂后发生甲状腺毒症是一种罕见情况。这种效应被称为碘致巴塞多效应，常在患有潜在甲状腺疾病的患者中出现，这些患者在接触外源性碘化物后发生甲状腺毒症。当为进行检查或操作而静脉给予大量碘化物时，可看到这种医源性病因的一个例子。甲状腺毒症还可导致心律失常，包括心房颤动。本文介绍了一例74岁女性病例，该患者在接受腹部诊断性CT的碘化造影剂后约一周出现甲状腺毒症以及新发心房颤动。我们还进一步回顾了此前发表的关于心房颤动和甲状腺毒症的文献。
