Rojas Francia, Valderrábano Miguel
Methodist DeBakey Heart and Vascular Center and Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas.
J Atr Fibrillation. 2013 Jun 30;6(1):886. doi: 10.4022/jafib.886. eCollection 2013 Jun-Jul.
Age has a great impact in the development of atrial fibrillation, which is the most common arrhythmia found in the elderly. The higher risk of stroke, heart failure and mortality associated with atrial fibrillation highlights the need for successful therapeutic interventions that can translate in better outcomes in this population. The introduction of catheter ablation has revolutionized the management of atrial fibrillation over the past decades with an undeniable impact in morbidity, mortality and quality of life. This benefit has not been fully extended to the older patients due to the lack of definitive data from randomized control trials assessing the impact ofrhythm control strategies such as catheter ablation in this population, in whom a rate-control strategy has been suggested as a better therapeutic option. In this review, we summarize the pathogenesis of atrial fibrillation in the elderly, the benefits and complications of catheter ablation reported in the literature and the impact of age in the outcomes of ablation compared to younger populations.
年龄对心房颤动的发展有很大影响，心房颤动是老年人中最常见的心律失常。与心房颤动相关的中风、心力衰竭和死亡风险较高，这凸显了成功的治疗干预措施的必要性，这些措施能够在该人群中带来更好的治疗效果。在过去几十年中，导管消融术的引入彻底改变了心房颤动的治疗方式，对发病率、死亡率和生活质量产生了不可否认的影响。由于缺乏评估诸如导管消融等节律控制策略对该人群影响的随机对照试验的确切数据，这种益处尚未完全惠及老年患者，在这一人群中，心率控制策略被认为是更好的治疗选择。在这篇综述中，我们总结了老年人心房颤动的发病机制、文献报道的导管消融的益处和并发症，以及与年轻人群相比年龄对消融结果的影响。
