冠状动脉慢血流患者的新型心室复极指标
Novel Ventricular Repolarization Indices in Patients with Coronary Slow Flow.
作者信息
Sucu Murat, Ucaman Berzal, Ozer Orhan, Altas Yakup, Polat Esra
机构信息
Gaziantep University School of Medicine, Department of Cardiology, Gaziantep Turkey.
Gazi Yasargil Training and Research Hospital, Department of Cardiology, Diyarbakır Turkey.
出版信息
J Atr Fibrillation. 2016 Oct 31;9(3):1446. doi: 10.4022/jafib.1446. eCollection 2016 Oct-Nov.
Coronary slow flow (CSF) phenomenon is described angiographically as delayed progression of the injected contrast agents through the coronary arteries. Aim of this study was to analyze ventricular repolarization in CSF patients by using Tpeak-Tend interval, Tpeak-Tend/QT ratio, Tpeak-Tend/QTc ratio and other repolarization parameters since these parameters are used as predictors for ventricular arrhythmogenesis. We have retrospectively analyzed diagnostic coronary angiography results of 160 patients between 2010 and 2014. Patients were divided into two groups according to coronary flow results. CSF group consisted of 33 female, 82 male patients with mean age 51,9±11,5 years. Control group included patients with normal coronary flow; 13 female, 32 male with mean age 50,8±11,7 years. In all patients, ventricular repolarization parameters as well as other associated electrocardiographic intervals were measured on the twelve-lead surface electrocardiogram. The ventricular repolarization parameters: QTmax interval, QTmin interval, QTc, QTI, QTcI, JTmax interval, JTmin interval, JTdispersion and JTIndex were not significantly different between the groups. However followings parameters differed significantly between patients and controls; QRS (92,8±11,5 msn versus 78,3±16,713,40 msn, respectively; p=0.001), T wave (89±20,2 msn vs. 73,3±13,3 msn respectively, p=0.001), QT dispersion (26,8±17,5 msn vs. 13,5±20,4 msn respectively, p=0.002), JTcorrected (331,6±39,8%; vs. 350,1±39,7% respectively; p=0.01). Furthermore; Tpeak-Tend duration (89±20,2 msn vs. 73,3±13,9 msn respectively; p=0.001), T wave (204±34,9 msn vs. 189,2±24,8 msn respectively; p=0.003), Tpeak-Tend/QT ratio (0,22±0,05 msn vs. 0,19±0,03 msn respectively, p=0.001) were significantly higher in patients compared to controls. Tpeak-Tend/QTc ratio was also significantly higher in the CSF group compared to the controls. (0,21±0,05 msn vs. 0,17±0,03 msn respectively, p =0.001). Ventricular repolarization parameters are prolonged in patients with CSF.
冠状动脉慢血流（CSF）现象在血管造影中表现为注入的造影剂在冠状动脉内延迟推进。本研究的目的是通过使用T峰 - T末间期、T峰 - T末/QT比值、T峰 - T末/QTc比值及其他复极参数来分析CSF患者的心室复极情况，因为这些参数被用作心室心律失常发生的预测指标。我们回顾性分析了2010年至2014年间160例患者的诊断性冠状动脉造影结果。根据冠状动脉血流结果将患者分为两组。CSF组包括33例女性和82例男性患者，平均年龄51.9±11.5岁。对照组包括冠状动脉血流正常的患者；13例女性和32例男性，平均年龄50.8±11.7岁。在所有患者中，在十二导联体表心电图上测量心室复极参数以及其他相关的心电图间期。两组之间的心室复极参数：QTmax间期、QTmin间期、QTc、QTI、QTcI、JTmax间期、JTmin间期、JT离散度和JT指数无显著差异。然而，患者与对照组之间以下参数存在显著差异；QRS（分别为92.8±11.5毫秒对78.3±16.713.40毫秒；p = 0.001），T波（分别为89±20.2毫秒对73.3±13.3毫秒，p = 0.001），QT离散度（分别为26.8±17.5毫秒对13.5±20.4毫秒，p = 0.002），JT校正值（分别为331.6±39.8%对350.1±39.7%；p = 0.01）。此外；T峰 - T末持续时间（分别为89±20.2毫秒对73.3±13.9毫秒；p = 0.001），T波（分别为204±34.9毫秒对189.2±24.8毫秒；p = 0.003），患者的T峰 - T末/QT比值（分别为0.22±0.05毫秒对0.19±0.03毫秒，p = 0.001）显著高于对照组。CSF组的T峰 - T末/QTc比值也显著高于对照组。（分别为0.21±0.05毫秒对0.17±0.03毫秒，p = 0.001）。CSF患者的心室复极参数延长。
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