Schmoch T, Bernhard M, Uhle F, Gründling M, Brenner T, Weigand M A
Klinik für Anästhesiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
Zentrale Notaufnahme, Universitätsklinikum Leipzig AöR, Leipzig, Deutschland.
Anaesthesist. 2017 Aug;66(8):614-621. doi: 10.1007/s00101-017-0316-2.
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) have been available since the beginning of 2016. SEPSIS-3 completely replaces the old SIRS criteria in the definition of sepsis and defines sepsis from now on as "life-threatening organ dysfunction caused by a dysregulated host response to infection". However, it seems questionable whether in clinical practice the new definition is really superior to the old one. The most important question is the following: Is it helpful to have a definition that first recognizes a patient once organ dysfunction has occurred and the patient already needs intensive care?
《脓毒症及脓毒性休克第三次国际共识定义》(Sepsis-3)自2016年初起开始使用。Sepsis-3在脓毒症定义中完全取代了旧的全身炎症反应综合征(SIRS)标准,从今往后将脓毒症定义为“宿主对感染的反应失调所导致的危及生命的器官功能障碍”。然而,在临床实践中,新定义是否真的优于旧定义似乎值得怀疑。最重要的问题如下:对于一个一旦发生器官功能障碍且患者已需要重症监护才被首次识别的定义,它有帮助吗?