Larson E
Johns Hopkins University, School of Nursing.
Am J Infect Control. 1988 Dec;16(6):253-66. doi: 10.1016/s0196-6553(88)80005-1.
This Guideline is based on published data available at the time of writing. The ideal means for comparing performance of various antimicrobial agents is through the conduct of carefully designed, large-scale clinical trials. Recommendations contained in this Guideline are subject to modification as additional data become available. It particularly should be noted that the implementation of universal precautions or body substance isolation has resulted in marked increase in the use of gloves for direct patient contact. Whether there is an additional cost-benefit rationale for handwashing with an antimicrobial agent remains to be studied.
本指南基于编写时可获取的已发表数据。比较各种抗菌药物性能的理想方法是通过开展精心设计的大规模临床试验。随着更多数据的出现，本指南中的建议可能会有所修改。特别需要注意的是，实施普遍预防措施或体液隔离已导致直接接触患者时手套的使用显著增加。使用抗菌剂洗手是否存在额外的成本效益依据仍有待研究。
