Dev Tanvi, Bhari Neetu, Naranje Priyanka, Sethuraman Gomathy
Department of Dermatology, All India Institute of Medical Sciences, New Delhi, India.
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
BMJ Case Rep. 2017 May 12;2017:bcr-2017-219511. doi: 10.1136/bcr-2017-219511.
Systemic inflammatory rheumatic diseases have shown an increase in frequency of internal malignancies, predominantly lymphoproliferative disorders. Occurrence of solid organ tumours is exceedingly rare. It is even rarer for it to manifest as recurrent syncope. We report a 55-year-old woman with systemic lupus erythematosus, who later developed episodes of syncope and dizziness along with diaphoresis and palpitations. She also had associated abdominal pain and vomiting. Imaging revealed a gall bladder (GB) mass with hepatic extension, which was histologically consistent with adenocarcinoma of the GB. Subsequently she succumbed to death during chemotherapy.
全身性炎性风湿性疾病患者发生内脏恶性肿瘤的频率有所增加,主要是淋巴增生性疾病。实体器官肿瘤的发生极为罕见。以反复晕厥为表现的情况更为罕见。我们报告一名55岁的系统性红斑狼疮女性患者,她后来出现晕厥、头晕发作,伴有出汗和心悸。她还伴有腹痛和呕吐。影像学检查发现胆囊(GB)肿物并侵犯肝脏,组织学检查结果与胆囊腺癌相符。随后,她在化疗期间死亡。